Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 203228
Gene Symbol: C9orf72
C9orf72 		Q96LT7 C9orf72-SMCR8 complex subunit 258 0.496 0.769 1.1E-06 0.100 None 0 0
Entrez Id: 54664
Gene Symbol: TMEM106B
TMEM106B 		Q9NUM4 transmembrane protein 106B 126 0.590 0.462 0.33 0.100 None 0 0
Entrez Id: 7415
Gene Symbol: VCP
VCP 		P55072 valosin containing protein 376 0.469 0.923 1.00 0.100 None 0 0
Entrez Id: 25978
Gene Symbol: CHMP2B
CHMP2B 		Q9UQN3 charged multivesicular body protein 2B 177 0.543 0.731 4.6E-06 0.100 None 0 0
Entrez Id: 6272
Gene Symbol: SORT1
SORT1 		Q99523 sortilin 1 Transporter 111 0.573 0.615 1.00 0.010 None < 0.001 1 0 2018 2018
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.020 None 0.500 2 0 1995 2000
Entrez Id: 2596
Gene Symbol: GAP43
GAP43 		P17677 growth associated protein 43 109 0.564 0.731 2.1E-02 0.020 None 0.500 2 0 1996 2000
Entrez Id: 54209
Gene Symbol: TREM2
TREM2 		Q9NZC2 triggering receptor expressed on myeloid cells 2 239 0.519 0.769 3.3E-09 0.130 None 0.667 3 0 2018 2019
Entrez Id: 836
Gene Symbol: CASP3
CASP3 		P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.040 None 0.750 4 0 1999 2016
Entrez Id: 4311
Gene Symbol: MME
MME 		P08473 membrane metalloendopeptidase Enzyme 470 0.407 0.808 1.5E-18 0.040 None 0.750 4 0 2001 2010
Entrez Id: 5621
Gene Symbol: PRNP
PRNP 		F7VJQ1 P04156 prion protein 426 0.445 0.923 6.3E-04 0.200 None 0.900 10 1 1991 2020
Entrez Id: 348
Gene Symbol: APOE
APOE 		P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.200 None 0.921 76 0 1993 2019
Entrez Id: 351
Gene Symbol: APP
APP 		P05067 amyloid beta precursor protein Enzyme modulator 485 0.422 0.846 4.7E-02 0.400 None 0.988 164 5 1988 2020
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		P10636 microtubule associated protein tau 469 0.446 0.923 6.0E-03 0.200 None 1.000 43 1 1993 2019
Entrez Id: 23621
Gene Symbol: BACE1
BACE1 		P56817 beta-secretase 1 Enzyme 120 0.559 0.769 0.88 0.100 None 1.000 20 0 2004 2019
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1 		P49768 presenilin 1 Enzyme 369 0.469 0.846 0.97 0.200 None 1.000 15 3 1996 2018
Entrez Id: 8803
Gene Symbol: SUCLA2
SUCLA2 		Q9P2R7 succinate-CoA ligase ADP-forming subunit beta Enzyme 136 0.566 0.654 2.3E-03 0.100 None 1.000 10 0 2011 2019
Entrez Id: 6622
Gene Symbol: SNCA
SNCA 		P37840 synuclein alpha Transporter 449 0.427 0.885 0.88 0.080 None 1.000 8 0 1999 2018
Entrez Id: 2670
Gene Symbol: GFAP
GFAP 		P14136 glial fibrillary acidic protein 447 0.421 0.885 1.5E-06 0.070 None 1.000 7 0 1987 2016
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		P23560 brain derived neurotrophic factor Signaling 992 0.345 0.923 0.66 0.060 None 1.000 6 0 2013 2019
Entrez Id: 12
Gene Symbol: SERPINA3
SERPINA3 		P01011 serpin family A member 3 Enzyme modulator 229 0.486 0.846 8.8E-14 0.050 None 1.000 5 0 1997 2004
Entrez Id: 3416
Gene Symbol: IDE
IDE 		P14735 insulin degrading enzyme Enzyme 71 0.604 0.577 6.6E-03 0.050 None 1.000 5 0 2003 2010
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2367 0.248 0.962 0.32 0.040 None 1.000 4 0 2000 2017
Entrez Id: 4353
Gene Symbol: MPO
MPO 		P05164 myeloperoxidase Enzyme 653 0.377 0.923 7.1E-15 0.040 None 1.000 4 0 1999 2019
Entrez Id: 102
Gene Symbol: ADAM10
ADAM10 		O14672 ADAM metallopeptidase domain 10 224 0.489 0.846 1.00 0.040 None 1.000 4 0 2012 2019