Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 1368 0.303 0.885 1.00 0.060 None 1.000 6 0 2007 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.050 None 1.000 5 0 2003 2018
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.040 None 1.000 4 0 2002 2014
Entrez Id: 8289
Gene Symbol: ARID1A
ARID1A
O14497 AT-rich interaction domain 1A 341 0.455 0.846 1.00 0.030 None 1.000 3 0 2013 2019
Entrez Id: 6928
Gene Symbol: HNF1B
HNF1B
P35680 HNF1 homeobox B Nucleic acid binding 279 0.473 0.808 1.00 0.110 None 1.000 2 1 2016 2019
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
P43246 mutS homolog 2 Nucleic acid binding 490 0.406 0.808 0.90 0.020 None 1.000 2 0 2004 2013
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
P52701 mutS homolog 6 Nucleic acid binding 296 0.462 0.731 3.7E-05 0.020 None 1.000 2 0 2004 2013
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
P40692 mutL homolog 1 Nucleic acid binding 526 0.399 0.808 3.4E-05 0.020 None 1.000 2 0 2004 2013
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
P17936 insulin like growth factor binding protein 3 Enzyme modulator 350 0.439 0.808 0.91 0.020 None 1.000 2 0 2008 2009
Entrez Id: 4360
Gene Symbol: MRC1
MRC1
P22897 mannose receptor C-type 1 431 0.413 0.846 0.94 0.020 None 1.000 2 0 2013 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.020 None 1.000 2 0 2017 2018
Entrez Id: 1781
Gene Symbol: DYNC1I2
DYNC1I2
Q13409 dynein cytoplasmic 1 intermediate chain 2 Cellular structure 34 0.760 0.385 1.1E-08 0.020 None 1.000 2 0 2017 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.010 None 1.000 1 0 2013 2013
Entrez Id: 84790
Gene Symbol: TUBA1C
TUBA1C
Q9BQE3 tubulin alpha 1c Cellular structure 35 0.663 0.577 7.4E-03 0.100 None 1.000 1 1 2016 2016
Entrez Id: 4437
Gene Symbol: MSH3
MSH3
P20585 mutS homolog 3 Nucleic acid binding 245 0.474 0.769 7.4E-31 0.010 None 1.000 1 0 2004 2004
Entrez Id: 4488
Gene Symbol: MSX2
MSX2
P35548 msh homeobox 2 Transcription factor 135 0.539 0.769 0.26 0.010 None 1.000 1 0 2011 2011
Entrez Id: 4580
Gene Symbol: MTX1
MTX1
Q13505 metaxin 1 124 0.546 0.731 1.3E-02 0.100 None 1.000 1 1 2016 2016
Entrez Id: 5241
Gene Symbol: PGR
PGR
P06401 progesterone receptor Nuclear receptor 392 0.426 0.885 5.1E-02 0.010 None 1.000 1 0 2017 2017
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.010 None 1.000 1 0 2015 2015
Entrez Id: 83878
Gene Symbol: USHBP1
USHBP1
Q8N6Y0 USH1 protein network component harmonin binding protein 1 21 0.705 0.269 3.0E-17 0.100 None 1.000 1 1 2016 2016
Entrez Id: 581
Gene Symbol: BAX
BAX
Q07812 BCL2 associated X, apoptosis regulator Signaling 420 0.417 0.885 0.32 0.010 None < 0.001 1 0 2003 2003
Entrez Id: 5395
Gene Symbol: PMS2
PMS2
P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 244 0.484 0.808 4.5E-27 0.010 None 1.000 1 0 2013 2013
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.100 None 1.000 1 2 2016 2016
Entrez Id: 5426
Gene Symbol: POLE
POLE
Q07864 DNA polymerase epsilon, catalytic subunit 151 0.526 0.731 8.0E-27 0.010 None 1.000 1 1 2014 2014
Entrez Id: 5518
Gene Symbol: PPP2R1A
PPP2R1A
P30153 protein phosphatase 2 scaffold subunit Aalpha Enzyme 104 0.588 0.577 0.98 0.010 None 1.000 1 0 2013 2013