Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 232 0.236 0.962 0.53 0.500 None 0.952 8 0 1991 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 270 0.248 0.962 0.32 0.400 None 0.966 5 0 1994 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 167 0.266 0.923 2.4E-05 0.400 None 0.947 4 0 1997 2020
Entrez Id: 3586
Gene Symbol: IL10
IL10 		P22301 interleukin 10 95 0.281 0.923 5.9E-03 0.400 None 0.815 3 0 2001 2020
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 179 0.287 0.962 3.7E-02 0.400 None 0.929 2 0 1994 2020
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		P10415 BCL2 apoptosis regulator Signaling 141 0.291 0.885 0.56 0.400 None 1.000 1 0 1994 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 98 0.292 0.923 1.00 0.500 None 0.984 2 1 2005 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 124 0.295 0.885 0.37 0.400 None 0.972 3 0 1994 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 130 0.303 0.885 1.00 0.600 None 0.979 2 0 1998 2020
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 182 0.305 0.923 0.26 1.000 strong 0.975 18 5 1972 2020
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 138 0.305 0.923 1.9E-17 0.400 None 0.984 1 0 1998 2020
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		P10145 C-X-C motif chemokine ligand 8 Signaling 109 0.310 0.962 2.7E-04 0.400 None 0.900 2 0 1999 2020
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		P31749 AKT serine/threonine kinase 1 Kinase 109 0.311 0.962 0.98 0.400 None 0.992 2 0 2000 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 239 0.314 0.962 1.00 0.400 None 0.974 5 0 1998 2019
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		P05019 insulin like growth factor 1 119 0.318 0.885 0.27 0.400 None 0.946 3 0 1993 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 115 0.319 0.846 1.00 0.360 None 1.000 2 0 2006 2018
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 9 0.319 0.885 1.00 0.400 None 0.984 1 0 2005 2020
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		P40763 signal transducer and activator of transcription 3 Nucleic acid binding 138 0.320 0.923 1.00 0.400 None 0.989 3 0 2000 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 164 0.320 0.923 7.9E-04 0.600 None 1.000 1 0 2005 2018
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		O00206 toll like receptor 4 80 0.321 0.962 4.6E-09 0.400 None 0.850 1 0 2004 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 11 0.322 0.885 1.00 0.400 None 0.984 1 0 2005 2020
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 113 0.324 0.962 1.00 0.400 None 0.970 2 0 1996 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 89 0.327 0.923 0.98 0.400 None 0.952 1 0 2000 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 83 0.328 0.923 6.0E-03 0.400 None 0.945 3 0 1992 2019
Entrez Id: 1636
Gene Symbol: ACE
ACE 		P12821 angiotensin I converting enzyme Enzyme 101 0.328 0.923 1.0E-37 0.400 None 0.833 1 0 2004 2019