Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.010 None 1.000 1 0 2017 2017
Entrez Id: 2688
Gene Symbol: GH1
GH1
P01241 growth hormone 1 Signaling 686 0.373 0.923 3.0E-02 0.010 None 1.000 1 0 2020 2020
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
P00441 superoxide dismutase 1 Enzyme 689 0.379 0.962 0.18 0.010 None 1.000 1 0 2010 2010
Entrez Id: 4803
Gene Symbol: NGF
NGF
P01138 nerve growth factor Signaling 616 0.391 0.885 0.82 0.040 None 1.000 4 0 1999 2019
Entrez Id: 7291
Gene Symbol: TWIST1
TWIST1
Q15672 twist family bHLH transcription factor 1 Transcription factor 559 0.397 0.846 0.34 0.010 None 1.000 1 0 2019 2019
Entrez Id: 1312
Gene Symbol: COMT
COMT
P21964 catechol-O-methyltransferase Enzyme 622 0.400 0.923 1.1E-06 0.030 None 1.000 3 0 2009 2014
Entrez Id: 2668
Gene Symbol: GDNF
GDNF
P39905 glial cell derived neurotrophic factor Signaling 409 0.434 0.885 0.20 0.010 None 1.000 1 0 2017 2017
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
P07550 adrenoceptor beta 2 G-protein coupled receptor 387 0.442 0.923 0.53 0.010 None 1.000 1 0 2020 2020
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2
P01563 interferon alpha 2 355 0.442 0.885 0.300 None 1.000 1 0 2002 2002
Entrez Id: 7442
Gene Symbol: TRPV1
TRPV1
Q8NER1 transient receptor potential cation channel subfamily V member 1 Ion channel 404 0.446 0.885 1.0E-16 0.010 None 1.000 1 1 2019 2019
Entrez Id: 5027
Gene Symbol: P2RX7
P2RX7
Q99572 purinergic receptor P2X 7 Ion channel 337 0.450 0.808 3.3E-11 0.010 None 1.000 1 0 2017 2017
Entrez Id: 9048
Gene Symbol: ARTN
ARTN
Q5T4W7 artemin Signaling 248 0.480 0.846 0.36 0.010 None 1.000 1 0 2017 2017
Entrez Id: 57556
Gene Symbol: SEMA6A
SEMA6A
Q9H2E6 semaphorin 6A Signaling 211 0.486 0.808 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 4036
Gene Symbol: LRP2
LRP2
P98164 LDL receptor related protein 2 254 0.491 0.846 1.00 0.010 None 1.000 1 0 2017 2017
Entrez Id: 24
Gene Symbol: ABCA4
ABCA4
P78363 ATP binding cassette subfamily A member 4 Transporter 227 0.493 0.769 5.3E-48 0.010 None 1.000 1 0 2019 2019
Entrez Id: 2191
Gene Symbol: FAP
FAP
Q12884 fibroblast activation protein alpha Enzyme 216 0.496 0.808 1.9E-28 0.010 None 1.000 1 0 2018 2018
Entrez Id: 6869
Gene Symbol: TACR1
TACR1
P25103 tachykinin receptor 1 G-protein coupled receptor 217 0.502 0.885 3.8E-04 0.010 None 1.000 1 0 2001 2001
Entrez Id: 116
Gene Symbol: ADCYAP1
ADCYAP1
P18509 adenylate cyclase activating polypeptide 1 Signaling 220 0.510 0.846 0.52 0.010 None 1.000 1 0 2019 2019
Entrez Id: 2643
Gene Symbol: GCH1
GCH1
P30793 GTP cyclohydrolase 1 Enzyme 254 0.511 0.846 0.90 0.010 None 1.000 1 0 2007 2007
Entrez Id: 3483
Gene Symbol: IGFALS
IGFALS
P35858 insulin like growth factor binding protein acid labile subunit Receptor 203 0.511 0.846 5.4E-11 0.010 None 1.000 1 0 2010 2010
Entrez Id: 7503
Gene Symbol: XIST
XIST
X inactive specific transcript 146 0.522 0.808 0.010 None 1.000 1 0 2018 2018
Entrez Id: 28954
Gene Symbol: REM1
REM1
O75628 RRAD and GEM like GTPase 1 177 0.531 0.885 5.3E-08 0.010 None 1.000 1 0 2018 2018
Entrez Id: 6335
Gene Symbol: SCN9A
SCN9A
Q15858 sodium voltage-gated channel alpha subunit 9 Ion channel 213 0.543 0.615 4.8E-19 0.100 None 1.000 19 1 2004 2019
Entrez Id: 2166
Gene Symbol: FAAH
FAAH
O00519 fatty acid amide hydrolase 177 0.545 0.692 4.4E-11 0.020 None 1.000 2 0 2020 2020
Entrez Id: 8989
Gene Symbol: TRPA1
TRPA1
O75762 transient receptor potential cation channel subfamily A member 1 Ion channel 160 0.546 0.846 7.2E-35 0.020 None 1.000 2 1 2013 2014