Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
P09601 heme oxygenase 1 666 0.381 0.923 9.7E-03 0.300 None 1.000 1 0 2000 2000
Entrez Id: 3918
Gene Symbol: LAMC2
LAMC2
Q13753 laminin subunit gamma 2 Enzyme modulator 602 0.389 0.923 2.9E-12 0.010 None 1.000 1 1 2019 2019
Entrez Id: 3481
Gene Symbol: IGF2
IGF2
P01344 insulin like growth factor 2 604 0.390 0.885 4.4E-02 0.300 None 1.000 1 0 2005 2005
Entrez Id: 9402
Gene Symbol: GRAP2
GRAP2
O75791 GRB2 related adaptor protein 2 538 0.394 0.923 1.5E-04 0.010 None 1.000 1 0 2017 2017
Entrez Id: 406938
Gene Symbol: MIR146A
MIR146A
microRNA 146a 505 0.398 0.885 0.300 None 1.000 2 0 2011 2015
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
P08069 insulin like growth factor 1 receptor Kinase 556 0.399 0.885 0.97 0.300 None 1.000 1 0 2005 2005
Entrez Id: 4311
Gene Symbol: MME
MME
P08473 membrane metalloendopeptidase Enzyme 470 0.407 0.808 1.5E-18 0.010 None 1.000 1 0 2016 2016
Entrez Id: 2353
Gene Symbol: FOS
FOS
P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 528 0.411 0.885 0.26 0.010 None < 0.001 1 0 1997 1997
Entrez Id: 2147
Gene Symbol: F2
F2
P00734 coagulation factor II, thrombin Enzyme 490 0.415 0.885 1.1E-03 0.300 None 1.000 1 0 1993 1993
Entrez Id: 581
Gene Symbol: BAX
BAX
Q07812 BCL2 associated X, apoptosis regulator Signaling 420 0.417 0.885 0.32 0.300 None 1.000 1 0 2008 2008
Entrez Id: 351
Gene Symbol: APP
APP
P05067 amyloid beta precursor protein Enzyme modulator 485 0.422 0.846 4.7E-02 0.500 None 0.984 125 21 1991 2020
Entrez Id: 7276
Gene Symbol: TTR
TTR
P02766 transthyretin Transporter 461 0.423 0.885 0.52 0.010 None 1.000 1 0 1994 1994
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
P00749 plasminogen activator, urokinase Enzyme 439 0.425 0.923 2.3E-06 0.300 None 0 0
Entrez Id: 1191
Gene Symbol: CLU
CLU
P10909 clusterin 412 0.426 0.885 7.8E-05 0.300 None 1.000 3 0 2009 2011
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
P49841 glycogen synthase kinase 3 beta Kinase 393 0.430 0.846 0.96 0.300 None 1.000 2 0 2007 2013
Entrez Id: 3643
Gene Symbol: INSR
INSR
P06213 insulin receptor Kinase 452 0.432 0.846 3.6E-05 0.300 None 1.000 1 0 2014 2014
Entrez Id: 1471
Gene Symbol: CST3
CST3
P01034 cystatin C 370 0.436 0.808 3.9E-03 0.310 None 1.000 3 0 1993 2007
Entrez Id: 3077
Gene Symbol: HFE
HFE
Q30201 homeostatic iron regulator 415 0.436 0.846 2.6E-08 0.300 None 1.000 2 0 2004 2006
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
P10635 cytochrome P450 family 2 subfamily D member 6 432 0.437 0.885 1.1E-25 0.300 None 1.000 1 0 1995 1995
Entrez Id: 1392
Gene Symbol: CRH
CRH
P06850 corticotropin releasing hormone Signaling 402 0.439 0.808 0.72 0.300 None 1.000 1 0 1995 1995
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
P17936 insulin like growth factor binding protein 3 Enzyme modulator 350 0.439 0.808 0.91 0.010 None 1.000 1 0 2014 2014
Entrez Id: 4210
Gene Symbol: MEFV
MEFV
O15553 MEFV innate immuity regulator, pyrin 410 0.440 0.885 1.0E-14 0.010 None 1.000 1 1 2007 2007
Entrez Id: 301
Gene Symbol: ANXA1
ANXA1
P04083 annexin A1 336 0.442 0.885 1.2E-07 0.010 None 1.000 1 0 2005 2005
Entrez Id: 3725
Gene Symbol: JUN
JUN
P05412 Jun proto-oncogene, AP-1 transcription factor subunit Transcription factor 344 0.442 0.885 6.0E-02 0.010 None 1.000 1 0 2005 2005
Entrez Id: 5621
Gene Symbol: PRNP
PRNP
F7VJQ1 P04156 prion protein 426 0.445 0.923 6.3E-04 0.320 None 1.000 3 2 2000 2007