Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.030 None 1.000 3 0 1997 2016
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.010 None 1.000 1 0 2013 2013
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.050 None 1.000 5 0 2004 2018
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.010 None 1.000 1 0 2014 2014
Entrez Id: 60
Gene Symbol: ACTB
ACTB
P60709 actin beta Cellular structure 1110 0.325 0.923 0.99 0.010 None 1.000 1 0 2016 2016
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
H3 histone pseudogene 10 769 0.350 0.846 0.040 None 1.000 4 0 2009 2018
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
Q00987 MDM2 proto-oncogene Nucleic acid binding 702 0.362 0.846 1.00 0.400 None 0.929 56 0 1994 2019
Entrez Id: 947
Gene Symbol: CD34
CD34
P28906 CD34 molecule 674 0.368 0.808 5.0E-06 0.010 None 1.000 1 0 2000 2000
Entrez Id: 857
Gene Symbol: CAV1
CAV1
Q03135 caveolin 1 Enzyme modulator 633 0.388 0.885 8.3E-03 0.010 None 1.000 1 0 2001 2001
Entrez Id: 3342
Gene Symbol: HTC2
HTC2
hypertrichosis 2 (generalized, congenital) 511 0.392 0.808 0.010 None 1.000 1 0 2008 2008
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
P08069 insulin like growth factor 1 receptor Kinase 556 0.399 0.885 0.97 0.010 None 1.000 1 0 2017 2017
Entrez Id: 1019
Gene Symbol: CDK4
CDK4
P11802 cyclin dependent kinase 4 Kinase 433 0.412 0.808 6.3E-02 0.600 None 0.950 20 0 2000 2019
Entrez Id: 6857
Gene Symbol: SYT1
SYT1
P21579 synaptotagmin 1 Transporter 460 0.412 0.846 0.60 0.010 None 1.000 1 0 2014 2014
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA
P16234 platelet derived growth factor receptor alpha Kinase 452 0.415 0.808 1.00 0.010 None 1.000 1 0 2013 2013
Entrez Id: 8091
Gene Symbol: HMGA2
HMGA2
P52926 high mobility group AT-hook 2 Nucleic acid binding 382 0.429 0.808 0.87 0.400 None 1.000 10 0 1997 2015
Entrez Id: 4288
Gene Symbol: MKI67
MKI67
P46013 marker of proliferation Ki-67 351 0.431 0.808 1.3E-28 0.020 None 1.000 2 0 2002 2015
Entrez Id: 10413
Gene Symbol: YAP1
YAP1
P46937 Yes associated protein 1 Enzyme modulator 374 0.432 0.808 1.00 0.010 None 1.000 1 0 2016 2016
Entrez Id: 57534
Gene Symbol: MIB1
MIB1
Q86YT6 mindbomb E3 ubiquitin protein ligase 1 Enzyme 329 0.438 0.769 3.4E-88 0.020 None 1.000 2 0 2002 2015
Entrez Id: 4763
Gene Symbol: NF1
NF1
P21359 neurofibromin 1 Enzyme modulator 380 0.440 0.885 0.90 0.300 None 1.000 1 0 2010 2010
Entrez Id: 3725
Gene Symbol: JUN
JUN
P05412 Jun proto-oncogene, AP-1 transcription factor subunit Transcription factor 344 0.442 0.885 6.0E-02 0.020 None 1.000 2 0 2009 2015
Entrez Id: 5925
Gene Symbol: RB1
RB1
P06400 RB transcriptional corepressor 1 Nucleic acid binding 339 0.444 0.885 1.00 0.010 None 1.000 1 0 2002 2002
Entrez Id: 6590
Gene Symbol: SLPI
SLPI
P03973 secretory leukocyte peptidase inhibitor Enzyme modulator 310 0.449 0.846 9.0E-04 0.010 None 1.000 1 0 2010 2010
Entrez Id: 1674
Gene Symbol: DES
DES
P17661 desmin 330 0.460 0.846 8.8E-03 0.010 None 1.000 1 0 2013 2013
Entrez Id: 1649
Gene Symbol: DDIT3
DDIT3
P35638 DNA damage inducible transcript 3 264 0.467 0.846 0.59 0.030 None 1.000 3 0 1994 2015
Entrez Id: 2521
Gene Symbol: FUS
FUS
P35637 FUS RNA binding protein Nucleic acid binding 301 0.470 0.846 1.00 0.020 None 1.000 2 0 2000 2015