Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.500 None 1.000 12 0 1995 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.190 None 1.000 9 0 2004 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.130 None 1.000 3 0 1997 2011
Entrez Id: 29126
Gene Symbol: CD274
CD274
Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.030 None 1.000 3 0 2018 2019
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
P04818 thymidylate synthetase Enzyme 406 0.425 0.846 0.72 0.030 None 1.000 3 0 2005 2019
Entrez Id: 9997
Gene Symbol: SCO2
SCO2
O43819 synthesis of cytochrome C oxidase 2 Enzyme 294 0.479 0.846 7.5E-07 0.020 None 1.000 2 0 2005 2015
Entrez Id: 1890
Gene Symbol: TYMP
TYMP
P19971 thymidine phosphorylase Enzyme 246 0.495 0.769 1.2E-04 0.020 None 1.000 2 0 2005 2015
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.020 None 1.000 2 0 2005 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.020 None 1.000 2 0 2015 2019
Entrez Id: 238
Gene Symbol: ALK
ALK
Q9UM73 ALK receptor tyrosine kinase Kinase 519 0.396 0.846 3.2E-06 0.020 None 1.000 2 0 2017 2018
Entrez Id: 5395
Gene Symbol: PMS2
PMS2
P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 244 0.484 0.808 4.5E-27 0.010 None 1.000 1 0 2010 2010
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.010 None 1.000 1 0 2012 2012
Entrez Id: 574456
Gene Symbol: MIR497
MIR497
microRNA 497 116 0.539 0.808 0.010 None 1.000 1 0 2009 2009
Entrez Id: 51435
Gene Symbol: SCARA3
SCARA3
Q6AZY7 scavenger receptor class A member 3 Receptor 34 0.674 0.462 3.0E-08 0.010 None 1.000 1 0 2012 2012
Entrez Id: 6520
Gene Symbol: SLC3A2
SLC3A2
P08195 solute carrier family 3 member 2 Transporter 108 0.565 0.731 4.2E-08 0.010 None 1.000 1 0 2019 2019
Entrez Id: 6606
Gene Symbol: SMN1
SMN1
Q16637 survival of motor neuron 1, telomeric Epigenetic regulator 317 0.454 0.769 1.6E-02 0.010 None 1.000 1 0 2017 2017
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
Q9UNQ0 ATP binding cassette subfamily G member 2 (Junior blood group) Transporter 420 0.419 0.885 2.1E-32 0.010 None 1.000 1 0 2012 2012
Entrez Id: 6607
Gene Symbol: SMN2
SMN2
Q16637 survival of motor neuron 2, centromeric 299 0.459 0.769 0.10 0.010 None 1.000 1 0 2017 2017
Entrez Id: 8140
Gene Symbol: SLC7A5
SLC7A5
Q01650 solute carrier family 7 member 5 Transporter 173 0.513 0.808 0.24 0.010 None 1.000 1 0 2019 2019
Entrez Id: 85406
Gene Symbol: DNAJC14
DNAJC14
Q6Y2X3 DnaJ heat shock protein family (Hsp40) member C14 11 0.805 0.423 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 94025
Gene Symbol: MUC16
MUC16
Q8WXI7 mucin 16, cell surface associated 236 0.479 0.808 8.3E-112 0.010 None 1.000 1 0 2018 2018
Entrez Id: 580
Gene Symbol: BARD1
BARD1
Q99728 BRCA1 associated RING domain 1 75 0.597 0.538 1.4E-24 0.110 None < 0.001 1 0 2017 2017
Entrez Id: 406971
Gene Symbol: MIR195
MIR195
microRNA 195 180 0.496 0.769 0.010 None 1.000 1 0 2009 2009
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 345 0.445 0.846 1.6E-07 0.010 None 1.000 1 0 2015 2015
Entrez Id: 142
Gene Symbol: PARP1
PARP1
P09874 poly(ADP-ribose) polymerase 1 565 0.389 0.923 3.3E-04 0.010 None 1.000 1 0 2015 2015