Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 51196
Gene Symbol: PLCE1
PLCE1
Q9P212 phospholipase C epsilon 1 Enzyme 114 0.572 0.654 5.7E-11 0.010 None < 0.001 1 3 2014 2014
Entrez Id: 100124700
Gene Symbol: HOTAIR
HOTAIR
HOX transcript antisense RNA 234 0.475 0.769 0.010 None < 0.001 1 0 2014 2014
Entrez Id: 7424
Gene Symbol: VEGFC
VEGFC
P49767 vascular endothelial growth factor C Signaling 291 0.459 0.769 0.50 0.010 None < 0.001 1 0 2018 2018
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 603 0.380 0.885 0.50 0.010 None < 0.001 1 0 2014 2014
Entrez Id: 1586
Gene Symbol: CYP17A1
CYP17A1
P05093 cytochrome P450 family 17 subfamily A member 1 326 0.462 0.769 2.6E-04 0.010 None < 0.001 1 2 2014 2014
Entrez Id: 2248
Gene Symbol: FGF3
FGF3
P11487 fibroblast growth factor 3 Signaling 200 0.505 0.808 9.3E-05 0.010 None < 0.001 1 0 2014 2014
Entrez Id: 1545
Gene Symbol: CYP1B1
CYP1B1
Q16678 cytochrome P450 family 1 subfamily B member 1 Enzyme 304 0.457 0.769 2.2E-05 0.020 None 0.500 2 0 2014 2014
Entrez Id: 5315
Gene Symbol: PKM
PKM
P14618 pyruvate kinase M1/2 Kinase 237 0.482 0.808 0.85 0.020 None 0.500 2 0 2016 2017
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.020 None 0.500 2 1 2008 2017
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.030 None 0.667 3 0 2015 2019
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
P09488 glutathione S-transferase mu 1 627 0.380 0.923 2.1E-03 0.040 None 0.750 4 0 2007 2019
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 Enzyme 1021 0.333 0.923 0.84 0.040 None 0.750 4 0 2012 2017
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.040 None 0.750 4 2 2014 2019
Entrez Id: 960
Gene Symbol: CD44
CD44
P16070 CD44 molecule (Indian blood group) 711 0.363 0.962 2.4E-07 0.040 None 0.750 4 0 2000 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.050 None 0.800 5 0 2009 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 0.842 19 4 1994 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.070 None 0.857 7 0 2009 2018
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 379 0.436 0.846 1.1E-17 0.080 None 0.875 8 1 2007 2014
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.100 None 1.000 10 0 2006 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.100 None 1.000 10 1 2004 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.080 None 1.000 8 0 2001 2019
Entrez Id: 6443
Gene Symbol: SGCB
SGCB
Q16585 sarcoglycan beta 64 0.656 0.346 9.6E-07 0.060 None 1.000 6 0 2012 2017
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.060 None 1.000 6 1 2015 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.060 None 1.000 6 2 2015 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.060 None 1.000 6 0 2015 2019