MOS significantly increased albumin permeation and <i>il1b, il6, il8, tnfa</i>, and <i>tgfb</i> expression, but suppressed ROS production, cell proliferation and <i>myd88</i> expression.
Lower albumin was significantly associated with older age and parameters reflecting more aggressive disease biology (e.g. anemia, lower platelet levels, higher lactate dehydrogenase (LDH), circulatory blasts, transfusion dependency, blast phase disease), inflammation (higher C reactive protein (CRP), constitutional symptoms) and higher degree of bone marrow fibrosis.