Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.300 Biomarker disease CTD_human Delayed resolution of acute inflammation during zymosan-induced arthritis in leptin-deficient mice. 15142272 2004
Entrez Id: 6863
Gene Symbol: TAC1
TAC1 		0.300 Biomarker disease CTD_human Twenty one days after induction of adjuvant arthritis, sciatic nerve levels of substance P were significantly increased whilst there was a small but non-significant increase in gamma-PPT mRNA and substance P in L4/L5 dorsal root ganglia (DRG). 9259450 1997
Entrez Id: 5734
Gene Symbol: PTGER4
PTGER4 		0.300 Biomarker disease CTD_human MF498 [N-{[4-(5,9-Diethoxy-6-oxo-6,8-dihydro-7H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylbenzyl]sulfonyl}-2-(2-methoxyphenyl)acetamide], a selective E prostanoid receptor 4 antagonist, relieves joint inflammation and pain in rodent models of rheumatoid and osteoarthritis. 18287210 2008
Entrez Id: 3605
Gene Symbol: IL17A
IL17A 		0.300 Biomarker disease CTD_human Cytokine-dependent but acquired immunity-independent arthritis caused by DNA escaped from degradation. 20974942 2010
Entrez Id: 3458
Gene Symbol: IFNG
IFNG 		0.300 Biomarker disease CTD_human Modulation of the oxidative stress and inflammatory cytokine response by thymoquinone in the collagen induced arthritis in Wistar rats. 22450443 2012
Entrez Id: 90865
Gene Symbol: IL33
IL33 		0.300 Biomarker disease CTD_human IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy. 20472598 2010
Entrez Id: 3458
Gene Symbol: IFNG
IFNG 		0.300 Biomarker disease CTD_human Heavy metal exposure reverses genetic resistance to Chlamydia-induced arthritis. 19203382 2009
Entrez Id: 1280
Gene Symbol: COL2A1
COL2A1 		0.300 Biomarker disease CTD_human Influence of heme oxygenase 1 modulation on the progression of murine collagen-induced arthritis. 16200597 2005
Entrez Id: 6424
Gene Symbol: SFRP4
SFRP4 		0.300 Biomarker disease CTD_human MicroRNA-152 modulates the canonical Wnt pathway activation by targeting DNA methyltransferase 1 in arthritic rat model. 25194984 2014
Entrez Id: 1280
Gene Symbol: COL2A1
COL2A1 		0.300 Biomarker disease CTD_human Effect of cadmium chloride exposure during the induction of collagen induced arthritis. 26070417 2015
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.300 Biomarker disease CTD_human Ameliorating effect of Kalpaamruthaa, a Siddha preparation in adjuvant induced arthritis in rats with reference to changes in proinflammatory cytokines and acute phase proteins. 19330884 2009
Entrez Id: 4982
Gene Symbol: TNFRSF11B
TNFRSF11B 		0.300 Therapeutic disease CTD_human RANKL targeted peptides inhibit osteoclastogenesis and attenuate adjuvant induced arthritis by inhibiting NF-κB activation and down regulating inflammatory cytokines. 23333834 2013
Entrez Id: 213
Gene Symbol: ALB
ALB 		0.300 Biomarker disease CTD_human IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy. 20472598 2010
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		0.300 Biomarker disease CTD_human Local activation of STAT-1 and STAT-3 in the inflamed synovium during zymosan-induced arthritis: exacerbation of joint inflammation in STAT-1 gene-knockout mice. 15188379 2004
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.300 Biomarker disease CTD_human Cilostazol enhances apoptosis of synovial cells from rheumatoid arthritis patients with inhibition of cytokine formation via Nrf2-linked heme oxygenase 1 induction. 20131233 2010
Entrez Id: 3596
Gene Symbol: IL13
IL13 		0.300 Therapeutic disease CTD_human Encapsulation in hollow fibres of xenogeneic cells engineered to secrete IL-4 or IL-13 ameliorates murine collagen-induced arthritis (CIA). 10444273 1999
Entrez Id: 1401
Gene Symbol: CRP
CRP 		0.300 Biomarker disease CTD_human Ameliorating effect of Kalpaamruthaa, a Siddha preparation in adjuvant induced arthritis in rats with reference to changes in proinflammatory cytokines and acute phase proteins. 19330884 2009
Entrez Id: 1280
Gene Symbol: COL2A1
COL2A1 		0.300 Biomarker disease CTD_human Metabolomic analysis of biochemical changes in the plasma and urine of collagen-induced arthritis in rats after treatment with Huang-Lian-Jie-Du-Tang. 24709313 2014
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.300 Biomarker disease CTD_human Methotrexate chronotherapy is effective against rheumatoid arthritis. 21452922 2011
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.300 Biomarker disease CTD_human Modulation of the oxidative stress and inflammatory cytokine response by thymoquinone in the collagen induced arthritis in Wistar rats. 22450443 2012
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		0.300 Biomarker disease CTD_human IL-1β and TNFα-initiated IL-6-STAT3 pathway is critical in mediating inflammatory cytokines and RANKL expression in inflammatory arthritis. 21937456 2011
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.300 Biomarker disease CTD_human Cytokine-dependent but acquired immunity-independent arthritis caused by DNA escaped from degradation. 20974942 2010
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1 		0.300 Biomarker disease CTD_human MicroRNA-152 modulates the canonical Wnt pathway activation by targeting DNA methyltransferase 1 in arthritic rat model. 25194984 2014
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.300 Biomarker disease CTD_human Modulation of the oxidative stress and inflammatory cytokine response by thymoquinone in the collagen induced arthritis in Wistar rats. 22450443 2012
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.300 Biomarker disease CTD_human Cytokine-dependent but acquired immunity-independent arthritis caused by DNA escaped from degradation. 20974942 2010