Gene: CCR6 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1235
Gene Symbol: CCR6
CCR6 		0.500 AlteredExpression disease BEFREE The CCR6DNP genotype was correlated with the expression level of CCR6 and was associated with the presence of interleukin-17 (IL-17) in the sera of subjects with rheumatoid arthritis. 20453841 2010
Entrez Id: 1235
Gene Symbol: CCR6
CCR6 		0.500 Biomarker disease CTD_human A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility. 20453841 2010
Entrez Id: 1235
Gene Symbol: CCR6
CCR6 		0.500 GeneticVariation disease GWASCAT A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility. 20453841 2010
Entrez Id: 1235
Gene Symbol: CCR6
CCR6 		0.500 GeneticVariation disease GWASDB Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. 20453842 2010
Entrez Id: 1235
Gene Symbol: CCR6
CCR6 		0.500 Biomarker disease CTD_human Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. 20453842 2010
Entrez Id: 1235
Gene Symbol: CCR6
CCR6 		0.500 GeneticVariation disease GWASCAT Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. 20453842 2010
Entrez Id: 1235
Gene Symbol: CCR6
CCR6 		0.500 Biomarker disease LHGDN Immunohistochemical analysis for CCR6, CCL20, and RANKL was performed on bone samples from RA patients. 17133360 2007
Entrez Id: 1235
Gene Symbol: CCR6
CCR6 		0.500 AlteredExpression disease BEFREE These results indicate that CCR6 expression contributes to Th17 cell function in autoimmune disease, especially in autoimmune arthritis such as RA. 18025126 2007
Entrez Id: 1235
Gene Symbol: CCR6
CCR6 		0.500 Biomarker disease BEFREE The ligand-receptor pair CCL20-CCR6 is responsible for the chemoattraction of immature dendritic cells (DC), effector/memory T-cells and B-cells and plays a role at skin and mucosal surfaces under homeostatic and inflammatory conditions, as well as in pathology, including cancer and rheumatoid arthritis. 12948524 2003
Entrez Id: 1235
Gene Symbol: CCR6
CCR6 		0.500 Biomarker disease BEFREE Overall, these studies indicate that MIP-3alpha and CCR6 may function to recruit monocytes and memory lymphocytes from the RA PB to the RA joint. 12695561 2003
Entrez Id: 1235
Gene Symbol: CCR6
CCR6 		0.500 AlteredExpression disease BEFREE Furthermore, expression of CCR6 was found in infiltrating mononuclear cells in the cellular clusters and around the vessels of RA synovial tissue. 11472439 2001