Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.090 Biomarker disease BEFREE Quantitative real-time polymerase chain reaction analysis, western blot analysis and immunohistochemistry were used to quantify renin, ACE, angiotensin type 1 and type 2 receptors, VEGF and MMP-13 in OA and RA. 31785770 2020
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.090 Biomarker disease BEFREE Primary prevention of myocardial infarction with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in hypertensive patients with rheumatoid arthritis-A nationwide cohort study. 29216228 2017
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.090 Biomarker disease BEFREE Heritability of RA was estimated as 62.2% and 56.1% in the AE and ACE models, respectively. 26727555 2016
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.090 GeneticVariation disease BEFREE Our meta-analysis demonstrates that the ACE I/D polymorphism is associated with susceptibility to RA, especially in Arab populations. 23413281 2015
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.090 GeneticVariation disease BEFREE Our study suggests that high frequency of the ACE D allele contributes to the heritability of RA susceptibility compared to other ACE alleles. 23981749 2013
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.090 GeneticVariation disease BEFREE As a result of our study, angiotensin converting enzyme gene I/D polymorphism DD genotype could be a genetic marker in rheumatoid arthritis in the Turkish study population. 23000565 2012
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.090 Biomarker disease BEFREE Association analysis of TNFR2, VDR, A2M, GSTT1, GSTM1, and ACE genes with rheumatoid arthritis in South Asians and Caucasians of East Midlands in the United Kingdom. 20401725 2011
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.090 GeneticVariation disease BEFREE Our study found an association between ACE deletion polymorphism and RA. 17985406 2007
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.090 GeneticVariation disease BEFREE Gene and genotype frequencies for the ACE-I/D polymorphism did not differ between those with early active severe and non-severe RA. 11036822 2000