This study aims to predict the diagnostic value of <sup>68</sup>Ga-citrate and <sup>18</sup>F-FDG PET/CT in RA by comparing and analyzing the value of <sup>68</sup>Ga-citrate and <sup>18</sup>F-FDG PET/CT for diagnosing type II collagen-induced arthritis (CIA) in rats.Some CIA models were established.
Traditional CV risk factors and RA disease characteristics (rheumatoid nodules and the Disease Activity Score in 28 joints using the C-reactive protein level in anti-CCP antibody-positive individuals) were independently associated with ascending aortic FDG uptake in RA patients without clinical CVD.
Several clinical studies of RA have demonstrated that FDG uptake in affected joints reflects the disease activity of RA, with strong correlations between FDG uptake and various clinical parameters having been noted.