Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8483
Gene Symbol: CILP
CILP 		0.010 Biomarker group BEFREE Autoimmunity to proteins, such as type II collagen and cartilage intermediate layer protein, that are produced by chondrocytes has been reported in patients with osteoarthritis (OA) as well as in patients with rheumatoid arthritis (RA). 15146421 2004
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1 		0.100 Biomarker group BEFREE Autoimmunity against neurofilament protein and its possible association with HLA-DRB1*1502 allele in glaucoma. 16005081 2005
Entrez Id: 7421
Gene Symbol: VDR
VDR 		0.100 GeneticVariation group BEFREE Autoimmune diseases and vitamin D receptor Apa-I polymorphism are associated with vitiligo in a small inbred Romanian community. 16710576 2006
Entrez Id: 57862
Gene Symbol: ZNF410
ZNF410 		0.010 GeneticVariation group BEFREE Autoimmune diseases and vitamin D receptor Apa-I polymorphism are associated with vitiligo in a small inbred Romanian community. 16710576 2006
Entrez Id: 169026
Gene Symbol: SLC30A8
SLC30A8 		0.100 GeneticVariation group BEFREE Autoimmunity against the COOH-terminal region of ZnT8 is a highly relevant prognostic feature in childhood type 1 diabetes. 19590848 2009
Entrez Id: 55532
Gene Symbol: SLC30A10
SLC30A10 		0.100 GeneticVariation group BEFREE Autoimmunity against the COOH-terminal region of ZnT8 is a highly relevant prognostic feature in childhood type 1 diabetes. 19590848 2009
Entrez Id: 284889
Gene Symbol: MIF-AS1
MIF-AS1 		0.030 Biomarker group BEFREE Autoimmune diseases: MIF as a therapeutic target. 20148714 2010
Entrez Id: 3119
Gene Symbol: HLA-DQB1
HLA-DQB1 		0.100 Biomarker group BEFREE Autoimmunity predominates in a large South African cohort with Addison's disease of mainly European descent despite long-standing disease and is associated with HLA DQB*0201. 20455895 2010
Entrez Id: 2332
Gene Symbol: FMR1
FMR1 		0.040 GeneticVariation group BEFREE Autoimmune disease in mothers with the FMR1 premutation is associated with seizures in their children with fragile X syndrome. 20809278 2010
Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1 		0.100 GeneticVariation group BEFREE Autoimmune disease risk variant of IFIH1 is associated with increased sensitivity to IFN-α and serologic autoimmunity in lupus patients. 21705624 2011
Entrez Id: 3447
Gene Symbol: IFNA13
IFNA13 		0.100 Biomarker group BEFREE Autoimmune disease risk variant of IFIH1 is associated with increased sensitivity to IFN-α and serologic autoimmunity in lupus patients. 21705624 2011
Entrez Id: 3439
Gene Symbol: IFNA1
IFNA1 		0.100 Biomarker group BEFREE Autoimmune disease risk variant of IFIH1 is associated with increased sensitivity to IFN-α and serologic autoimmunity in lupus patients. 21705624 2011
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2 		0.050 Biomarker group BEFREE Autoimmunity against the β2 adrenergic receptor and muscarinic-2 receptor in complex regional pain syndrome. 21816540 2011
Entrez Id: 326
Gene Symbol: AIRE
AIRE 		0.100 Biomarker group BEFREE Autoimmunity in patients with APECED syndrome has been shown to result from deficiency of AIRE function in transcriptional regulation of thymic peripheral tissue antigens, which leads to defective T-cell negative selection. 21962774 2012
Entrez Id: 4359
Gene Symbol: MPZ
MPZ 		0.020 Biomarker group BEFREE Autoimmunity against peripheral nerves in both mice and humans targets myelin protein zero, an Ag for which expression is Aire-regulated in the thymus. 22490868 2012
Entrez Id: 10666
Gene Symbol: CD226
CD226 		0.200 GeneticVariation group BEFREE Autoimmune disease-associated CD226 gene variants are not involved in giant cell arteritis susceptibility in the Spanish population. 22512842 2012
Entrez Id: 84329
Gene Symbol: HVCN1
HVCN1 		0.010 Biomarker group BEFREE Autoimmune disorder phenotypes in Hvcn1-deficient mice. 23231444 2013
Entrez Id: 723961
Gene Symbol: INS-IGF2
INS-IGF2 		0.130 AlteredExpression group BEFREE Autoimmunity against INS-IGF2 protein expressed in human pancreatic islets. 23935095 2013
Entrez Id: 1285
Gene Symbol: COL4A3
COL4A3 		0.030 Biomarker group BEFREE Autoimmunity against the Goodpasture antigen α3IV-NC1 results in crescentic glomerulonephritis (GN). 25965582 2015
Entrez Id: 7732
Gene Symbol: RNF112
RNF112 		0.010 GeneticVariation group BEFREE Autoimmune diseases or serologic changes are known to have affected relatives of 5 patients, including 4 who had 1 or more relatives with BFP reactions. 2646509 1989
Entrez Id: 116372
Gene Symbol: LYPD1
LYPD1 		0.010 GeneticVariation group BEFREE Autoimmunity and peripheral lymphoid hyperplasia were found in 43% of 79 patients with PHTS. 27477328 2017
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3 		0.100 AlteredExpression group BEFREE Autoimmunity is linked to changes in FOXP3 activity that can occur at multiple levels and lead to Treg dysfunction. 27544816 2016
Entrez Id: 51182
Gene Symbol: HSPA14
HSPA14 		0.100 Biomarker group BEFREE Autoimmunity to HSP60 during diet induced obesity in mice. 27899808 2017
Entrez Id: 23515
Gene Symbol: MORC3
MORC3 		0.020 Biomarker group BEFREE Autoimmunity tests showed positivity for antinuclear antibodies and anti-NXP2, a recently described antibody associated with juvenile DM and, more rarely, with paraneoplastic DM. 28045754 2017
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.100 Biomarker group BEFREE Autoimmunity and inflammation are controlled in part by regulatory B (Breg) cells, including the recently identified IL-10-competent B10 cell subset that represents 1%-3% of mouse spleen B cells. 28110075 2017