Gene: IL10 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.700 Biomarker disease BEFREE Treg and Th17 cell frequencies and Th17 RORγt expression were significantly elevated, and IL-10 concentration in Treg cell supernatants was significantly lower in BD patients than in controls. 30601931 2019
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.700 GeneticVariation disease BEFREE The objective of the present study was to clarify the pathological roles of CCR1 and IL10 loci identified by previous BD genome-wide association studies (GWASs). 29895319 2018
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.700 Biomarker disease BEFREE Our aim was to fully examine the relationship between IL-10 and BD, the associations between BD and single nucleotide polymorphisms (SNPs) in IL-10-mediated signalling pathways (JAK1, TYK2, and STAT3) were examined in Korean patients with BD. 24428981 2014
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.700 AlteredExpression disease BEFREE The proinflammatory cytokines versus IL-10 ratios were significantly higher in BD compared with other groups. 21334264 2011
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.700 Biomarker disease BEFREE HBV: hepatitis B virus; HCC hepatocellular carcinoma; TNFSF10: tumor necrosis factor superfamily member 10; ATG5: autophagy-related protein 5; DNA: deoxyribonucleic acid; LDR-PCR: ligase detection reactions-polymerase chain reaction; PCR: polymerase chain reaction; SLE: systemic lupus erythematosus; BD: Behçet's disease; IL-10: interlukin-10; LPS: lipopolysaccharide; PBMC: peripheral blood mononuclear cells; CWP: coal workers' pneumoconiosis; TNF-α: tumor necrosis factor-α. 30907204 2019
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.700 AlteredExpression disease BEFREE The same difference was observed in IL-10 levels in culture supernatant after T. Baseline TLR4 expression was significantly higher in BD patients compared to healthy donors (HC). 27467286 2016
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.700 Biomarker disease BEFREE Although we were not able to formally replicate the association with IL10 and IL23R-IL12RB2, we do report that BD in Iran is strongly associated with HLA-B*51, MICA-A6, and the three HLA-linked SNPs (odds ratio (OR) = 3.38, P = 6.21 × 10(-14); OR = 2.08, P = 1.58 × 10(-13); and OR = 1.67-4.05, P = 1.45 × 10(-04) to 4.79 × 10(-34), respectively). 25940109 2015
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.700 GeneticVariation disease BEFREE Interleukin-10 gene polymorphisms are associated with Behcet's disease but not with Vogt-Koyanagi-Harada syndrome in the Chinese Han population. 26015771 2015
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.700 Biomarker disease BEFREE Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease. 20622878 2010
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.700 GeneticVariation disease BEFREE These results suggest that TGF-Beta1 and IL-10 gene polymorphisms may affect host susceptibility to BD. 19796538 2010
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.700 Biomarker disease CTD_human Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behçet's disease susceptibility loci. 20622879 2010
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.700 Biomarker disease CTD_human Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease. 20622878 2010
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.700 GeneticVariation disease GWASCAT Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behçet's disease susceptibility loci. 20622879 2010
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.700 GeneticVariation disease GWASCAT Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease. 20622878 2010
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.700 SusceptibilityMutation disease ORPHANET Interleukin-10 gene polymorphisms are associated with Behcet's disease but not with Vogt-Koyanagi-Harada syndrome in the Chinese Han population. 26015771 2015
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.700 SusceptibilityMutation disease ORPHANET Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease. 20622878 2010
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.700 GeneticVariation disease GWASDB Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease. 20622878 2010
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.700 GeneticVariation disease GWASDB Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1. 23291587 2013
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.700 GeneticVariation disease GWASDB Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behçet's disease susceptibility loci. 20622879 2010