Gene: GSK3B ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B 		0.600 Biomarker disease PSYGENET The GSK-3β gene, GSK3B, codes for an enzyme that is a target for the action of mood stabilizers, lithium and possibly valproic acid.In this study, the relationship between haplotypes consisting of single nucleotide polymorphisms (SNPs) of GSK3B -50T/C and -1727A/T and the effect of lithium was studied among Japanese bipolar disorder lithium nonresponders and responders.The distributions of the GSK3B haplotypes (-50T/C and -1727A/T) showed a trend for significant difference between the lithium nonresponders and responders (global P=0.07074). 24992082 2015
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B 		0.600 Biomarker disease CTD_human Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances. 20357757 2010
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B 		0.600 GeneticVariation disease LHGDN Further evidence on the lack of association between glycogen synthase kinase 3beta gene polymorphisms and bipolar disorder. 17621172 2007
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B 		0.600 Biomarker disease PSYGENET Lithium and GSK3-β promoter gene variants influence white matter microstructure in bipolar disorder. 22990942 2013