In addition, down-regulated LINC01605 in BC cells could significantly inhibit the abilities of proliferation, migration, and invasion <i>in vitro</i> and knockdown of LINC01605 in subcutaneous xenograft tumor model could impede tumorigenesis <i>in vivo</i> Mechanistically, LINC01605 could activate epithelial-mesenchymal transition (EMT) signaling pathway and promote the expression of matrix metallopeptidase (MMP) 9 (MMP9).