| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | Biomarker | group | BEFREE | CEA concentrations exceeding 5 ng/mL cut-off point indicated carcinomas, regardless of pleural involvement, which gave a sensitivity of 62% and specificity of 100% for carcinoma. | 31028099 | 2019 | ||||
|
0.090 | Biomarker | group | BEFREE | AA-Cur elicited moderate anti-tumor activity toward colon MC38-CEA or breast 4T1 carcinomas. | 31564877 | 2019 | ||||
|
0.090 | Biomarker | group | BEFREE | A phase I study of recombinant (r) vaccinia-CEA(6D)-TRICOM and rFowlpox-CEA(6D)-TRICOM vaccines with GM-CSF and IFN-α-2b in patients with CEA-expressing carcinomas. | 27581603 | 2016 | ||||
|
0.090 | AlteredExpression | group | BEFREE | PANVAC consists of rV, rF-CEA-MUC1-TRICOM; the expression of the two pan-carcinoma transgenes CEA and MUC-1 renders PANVAC vaccination applicable for therapeutic applications for a range of human carcinomas. | 22595052 | 2012 | ||||
|
0.090 | Biomarker | group | BEFREE | The objective of this study was both to design recombinant vectors in which the suicide gene E. coli purine nucleoside phosphorylase (ePNP) is under the control of either CEA or MUC1 promoter sequences and to investigate on experimental pancreatic carcinomas the selective killing effects of the conditional ePNP/prodrug (MePdR) system. | 15580629 | 2005 | ||||
|
0.090 | GeneticVariation | group | BEFREE | Phase I study of sequential vaccinations with fowlpox-CEA(6D)-TRICOM alone and sequentially with vaccinia-CEA(6D)-TRICOM, with and without granulocyte-macrophage colony-stimulating factor, in patients with carcinoembryonic antigen-expressing carcinomas. | 15613691 | 2005 | ||||
|
0.090 | Biomarker | group | BEFREE | CEA is an important tumor marker for colorectal and some other carcinomas. | 10202129 | 1999 | ||||
|
0.090 | AlteredExpression | group | BEFREE | Similarly to the 180 kd CEA molecules synthesized by carcinomas, the expression of the melanoma associated CEA like components (MA-CEA) is upregulated by IFN-alpha. | 3235849 | 1989 | ||||
|
0.090 | AlteredExpression | group | BEFREE | Pre-operative CEA levels were measured in 100 patients with large bowel carcinomas with different DNA ploidy pattern and serial post-operative determinations performed in the 64 who had been operated for cure. | 3816909 | 1986 |