| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | Biomarker | disease | BEFREE | Integrative clinical transcriptome analysis reveals TMPRSS2-ERG dependency of prognostic biomarkers in prostate adenocarcinoma. | 31732966 | 2020 | ||||
|
0.090 | Biomarker | disease | BEFREE | TMPRSS2/ERG fusion was found to be the most common genetic event in prostate adenocarcinoma. | 28550496 | 2017 | ||||
|
0.090 | Biomarker | disease | BEFREE | ERG and PTEN have been suggested as potential prognostic markers in prostatic adenocarcinoma. | 27913052 | 2017 | ||||
|
0.090 | Biomarker | disease | BEFREE | Within the IDC-P group, ERG status and PTEN status were similar among IDC-P, AIP and PCa in 96% and 91% of cases, respectively. | 28570007 | 2017 | ||||
|
0.090 | Biomarker | disease | BEFREE | We performed a molecular case study in which we studied mutation profiles of six tumor-associated HGPIN lesions in a single case of TMPRSS2:ERG fusion positive Gleason score 7 PCa that we had previously mapped for somatic mutations in adjacent Gleason patterns 3 and 4 foci, using microdissection and targeted deep-sequencing. | 27272561 | 2016 | ||||
|
0.090 | Biomarker | disease | BEFREE | The TMPRSS2-ERG fusion is a common chromosomal rearrangement that occurs early in the development of invasive adenocarcinoma of the prostate and results in the expression of a truncated ERG protein. | 23664537 | 2013 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | Prognostic potential of ERG (ETS-related gene) expression in prostatic adenocarcinoma. | 23686669 | 2013 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | In concordance with these findings, transgenic overexpression of ERG in mouse prostate tissue promotes marked acceleration and progression of high-grade prostatic intraepithelial neoplasia (HGPIN) to prostatic adenocarcinoma in a Pten heterozygous background. | 19396168 | 2009 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Given recent suggestions of TMPRSS2-ERG gene fusion association with aggressive prostatic adenocarcinoma, we evaluated the incidence of TMPRSS2-ERG fusion in minute prostatic adenocarcinomas. | 19734849 | 2009 |