×
Entrez Id:
55384
Gene Symbol:
MEG3
MEG3
0.100
Biomarker
disease
BEFREE
Our data suggested MEG3 was involved in stem cell-like state of LCCs and curbed migration and invasion through miR-650/SLC34A2 axis in NSCLC .
31585300
2019
×
Entrez Id:
55384
Gene Symbol:
MEG3
MEG3
0.100
AlteredExpression
disease
BEFREE
All these experiments were designed to investigate whether lncRNA MEG3 participated in the pathogenesis of NSCLC through inhibiting the expression of BRCA1 and Bcl-2 and promoting Bax expression.
30280775
2018
×
Entrez Id:
55384
Gene Symbol:
MEG3
MEG3
0.100
AlteredExpression
disease
BEFREE
PTX significantly inhibited the proliferation of NSCLC cells and increased the expressions of MEG3 and P53.
30173893
2018
×
Entrez Id:
55384
Gene Symbol:
MEG3
MEG3
0.100
Biomarker
disease
BEFREE
Mouse NSCLC transplanted tumor was established to verify the functional role of MEG3 in DDP resistance in vivo.
29123412
2017
×
Entrez Id:
55384
Gene Symbol:
MEG3
MEG3
0.100
AlteredExpression
disease
BEFREE
However, the association between MEG3 expression and prognosis in non-small cell lung cancer (NSCLC ) has not been fully investigated.
28782577
2017
×
Entrez Id:
55384
Gene Symbol:
MEG3
MEG3
0.100
AlteredExpression
disease
BEFREE
In this study, we identified the expressing difference of several tumor-related lncRNAs in breast cancer samples and found that, MEG3 , which is downregulated in non-small cell lung cancer (NSCLC ) tumor tissues, is also downregulated in breast cancer samples compared with adjacent tissues.
27166155
2016
×
Entrez Id:
55384
Gene Symbol:
MEG3
MEG3
0.100
Biomarker
disease
BEFREE
We therefore performed a meta-analysis on six lncRNAs (PVT1, AFAP1-AS1, LINC01133, ANRIL, MEG3 and UCA1) to clarify their prognostic roles in NSCLC .
27833074
2016
×
Entrez Id:
55384
Gene Symbol:
MEG3
MEG3
0.100
AlteredExpression
disease
BEFREE
The levels of Meg3 and Skp2 were inversely correlated in NSCLC specimens.
26482610
2016
×
Entrez Id:
55384
Gene Symbol:
MEG3
MEG3
0.100
Biomarker
disease
BEFREE
In conclusion, these results suggested that Meg3 may have a crucial role in the development of cisplatin resistance in non-small cell lung cancer .
26059239
2015
×
Entrez Id:
55384
Gene Symbol:
MEG3
MEG3
0.100
AlteredExpression
disease
BEFREE
NSCLC cells transfected with pCDNA-MEG3 were injection into nude mice to study the effect of MEG3 on tumorigenesis in vivo .
24098911
2013