Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
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0.070 | AlteredExpression | disease | BEFREE | We identified that miR-31 directly targeted SIRT3 in OSCC cells, and a reverse correlation between miR-31 expression and SIRT3 expression was noted in OSCC tumors. | 31055111 | 2019 | ||||
|
0.070 | Biomarker | disease | BEFREE | The resulting hypothesis is possible that the tissue-specific features of adenocarcinoma and squamous cell cancer and the positive feedback loop consists of miR-31 and its upstream and downstream may account for the diversity of miR-31 functions. | 30372817 | 2018 | ||||
|
0.070 | Biomarker | disease | BEFREE | We demonstrate that miR-31 is significantly decreased in invasive esophageal cancer cells, while upregulation of miR-31 inhibits growth, migration and invasion of esophageal adenocarcinoma (EAC) and squamous cell carcinoma (ESCC) cell lines. miR-31, in turn, targets SOX4 for degradation by directly binding to its 3'-UTR. | 25644061 | 2015 | ||||
|
0.070 | Biomarker | disease | BEFREE | miR-31(*) is a functional miRNA involving in regulating RhoA, and the activity of miR-31(*)'s activity seems to counteract the functions of miR-31 during OSCC tumorigenesis. | 22854067 | 2013 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | In comparison to normal epithelium, miR-21 was overexpressed in both VC and SCC and miR-31 was overexpressed in VC and in well- and moderately differentiated SCC. | 22690848 | 2012 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | We also showed that high expression of hsa-miR-31 was associated with poor survival in these 60 SCC patients by Kaplan-Meier analysis (P = 0.007), by univariate Cox analysis (P = 0.011), and by multivariate Cox analysis (P = 0.011). | 21890451 | 2011 | ||||
|
0.070 | Biomarker | disease | BEFREE | miR-31 in plasma was significantly elevated in OSCC patients relative to age and sex-matched control individuals. | 20233326 | 2010 |