Gene: TNNT2 ×
Source: CLINVAR ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Usefulness of running wheel for detection of congestive heart failure in dilated cardiomyopathy mouse model. 23383212 2013
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Severe disease expression of cardiac troponin C and T mutations in patients with idiopathic dilated cardiomyopathy. 15542288 2004
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Cardiac structural and sarcomere genes associated with cardiomyopathy exhibit marked intolerance of genetic variation. 23074333 2012
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 GeneticVariation group CLINVAR Clinical and functional characterization of TNNT2 mutations identified in patients with dilated cardiomyopathy. 20031601 2009
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 GeneticVariation group CLINVAR Mutations in sarcomere protein genes in left ventricular noncompaction. 18506004 2008
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Novel cardiac troponin T mutation as a cause of familial dilated cardiomyopathy. 11684629 2001
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Recurrent and founder mutations in the Netherlands: mutation p.K217del in troponin T2, causing dilated cardiomyopathy. 20978592 2010
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Dilated and hypertrophic cardiomyopathy mutations in troponin and alpha-tropomyosin have opposing effects on the calcium affinity of cardiac thin filaments. 17932326 2007
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 GeneticVariation group CLINVAR Genetic testing for dilated cardiomyopathy in clinical practice. 22464770 2012
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 GeneticVariation group CLINVAR Novel troponin T mutation in familial dilated cardiomyopathy with gender-dependant severity. 15464434 2005
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 GeneticVariation group CLINVAR Targeted panel sequencing in pediatric primary cardiomyopathy supports a critical role of TNNI3. 31568572 2019
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 GeneticVariation group CLINVAR RIKADA Study Reveals Risk Factors in Pediatric Primary Cardiomyopathy. 31333075 2019
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 GeneticVariation group CLINVAR Severe disease expression of cardiac troponin C and T mutations in patients with idiopathic dilated cardiomyopathy. 15542288 2004
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Whole exome sequencing identifies a troponin T mutation hot spot in familial dilated cardiomyopathy. 24205113 2013
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Effects of troponin T cardiomyopathy mutations on the calcium sensitivity of the regulated thin filament and the actomyosin cross-bridge kinetics of human β-cardiac myosin. 24367593 2013
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Poor prognosis of rare sarcomeric gene variants in patients with dilated cardiomyopathy. 24119082 2013
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 GeneticVariation group CLINVAR Coding sequence mutations identified in MYH7, TNNT2, SCN5A, CSRP3, LBD3, and TCAP from 313 patients with familial or idiopathic dilated cardiomyopathy. 19412328 2008
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Mutations in sarcomere protein genes in left ventricular noncompaction. 18506004 2008