Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 283234
Gene Symbol: CCDC88B
CCDC88B 		0.100 GeneticVariation disease GWASCAT Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease. 27992413 2017
Entrez Id: 6352
Gene Symbol: CCL5
CCL5 		0.010 GeneticVariation disease LHGDN The RANTES -28 g polymorphism is associated with primary sclerosing cholangitis. 17519498 2007
Entrez Id: 729230
Gene Symbol: CCR2
CCR2 		0.010 GeneticVariation disease BEFREE Pharmacological inhibition of monocyte recruitment by CVC treatment or CCR2 genetic deletion attenuated macrophage accumulation, liver injury and fibrosis in acute SC. 29802947 2018
Entrez Id: 1234
Gene Symbol: CCR5
CCR5 		0.010 GeneticVariation disease LHGDN Similarly, CCR5-Delta32 allele frequency was significantly higher in sclerosing cholangitis (17.6%) compared to controls (9.9%, OR 2.47, P=0.007) and inflammatory bowel disease patients without sclerosing cholangitis (11.3%, OR 1.9, P=0.027). 15215889 2004
Entrez Id: 1234
Gene Symbol: CCR5
CCR5 		0.010 GeneticVariation disease BEFREE Similarly, CCR5-Delta32 allele frequency was significantly higher in sclerosing cholangitis (17.6%) compared to controls (9.9%, OR 2.47, P=0.007) and inflammatory bowel disease patients without sclerosing cholangitis (11.3%, OR 1.9, P=0.027). 15215889 2004
Entrez Id: 102724297
Gene Symbol: CCR5AS
CCR5AS 		0.100 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 10666
Gene Symbol: CD226
CD226 		0.100 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 10666
Gene Symbol: CD226
CD226 		0.100 GeneticVariation disease GWASCAT Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease. 27992413 2017
Entrez Id: 10666
Gene Symbol: CD226
CD226 		0.100 GeneticVariation disease GWASCAT Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis. 23603763 2013
Entrez Id: 958
Gene Symbol: CD40
CD40 		0.100 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 923
Gene Symbol: CD6
CD6 		0.100 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1 		0.100 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.010 GeneticVariation disease LHGDN p16INK4a promoter mutations are frequent in primary sclerosing cholangitis (PSC) and PSC-associated cholangiocarcinoma. 12360471 2002
Entrez Id: 1080
Gene Symbol: CFTR
CFTR 		0.040 Biomarker disease LHGDN Primary sclerosing cholangitis in childhood is associated with abnormalities in cystic fibrosis-mediated chloride channel function. 17719933 2007
Entrez Id: 1080
Gene Symbol: CFTR
CFTR 		0.040 GeneticVariation disease LHGDN What is the role of cystic fibrosis transmembrane conductance regulator dysfunction in primary sclerosing cholangitis? 17719926 2007
Entrez Id: 1080
Gene Symbol: CFTR
CFTR 		0.040 Biomarker disease LHGDN Cystic fibrosis transmembrane conductance regulator gene polymorphisms in patients with primary sclerosing cholangitis. 18992954 2009
Entrez Id: 1080
Gene Symbol: CFTR
CFTR 		0.040 Biomarker disease LHGDN Increased prevalence of CFTR mutations and variants and decreased chloride secretion in primary sclerosing cholangitis. 12783301 2003
Entrez Id: 4261
Gene Symbol: CIITA
CIITA 		0.100 Biomarker disease HPO
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A 		0.100 GeneticVariation disease GWASCAT Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease. 27992413 2017
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A 		0.100 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 152100
Gene Symbol: CMC1
CMC1 		0.100 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 80315
Gene Symbol: CPEB4
CPEB4 		0.100 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 1390
Gene Symbol: CREM
CREM 		0.100 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.010 Biomarker disease BEFREE To generalize these observations, we suppressed β-catenin in Mdr2 knockout (KO) mice, which develop sclerosing cholangitis due to regurgitation of BA from leaky ducts. 31489648 2019
Entrez Id: 1611
Gene Symbol: DAP
DAP 		0.100 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016