Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 57544
Gene Symbol: TXNDC16
TXNDC16 		0.100 GeneticVariation disease GWASDB Genome wide study of maternal and parent-of-origin effects on the etiology of orofacial clefts. 22419666 2012
Entrez Id: 8458
Gene Symbol: TTF2
TTF2 		0.010 GeneticVariation disease BEFREE We performed a genetic analysis of the TTF-2 gene in 2 children with congenital hypothyroidism (CH) and cleft palate, 45 children with thyroid dysgenesis, 19 children with isolated cleft palate or cleft lip, 4 patients with thyroid hemiagenesis. 15320969 2004
Entrez Id: 8295
Gene Symbol: TRRAP
TRRAP 		0.100 Biomarker disease HPO
Entrez Id: 80342
Gene Symbol: TRAF3IP3
TRAF3IP3 		0.100 GeneticVariation disease GWASDB A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4. 20436469 2010
Entrez Id: 80342
Gene Symbol: TRAF3IP3
TRAF3IP3 		0.100 GeneticVariation disease GWASDB Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. 22863734 2012
Entrez Id: 8626
Gene Symbol: TP63
TP63 		0.720 SusceptibilityMutation disease ORPHANET A mutation of the p63 gene in non-syndromic cleft lip. 16740912 2006
Entrez Id: 8626
Gene Symbol: TP63
TP63 		0.720 GeneticVariation disease BEFREE A mutation of the p63 gene in non-syndromic cleft lip. 16740912 2006
Entrez Id: 8626
Gene Symbol: TP63
TP63 		0.720 GeneticVariation disease BEFREE Ankyloblepharon-ectodermal defect-cleft lip and/or palate (AEC) is a rare genetic disorder due to mutations in the TP63 gene. 19676058 2009
Entrez Id: 8626
Gene Symbol: TP63
TP63 		0.720 Biomarker disease HPO
Entrez Id: 8626
Gene Symbol: TP63
TP63 		0.720 GeneticVariation disease LHGDN A mutation of the p63 gene in non-syndromic cleft lip. 16740912 2006
Entrez Id: 8626
Gene Symbol: TP63
TP63 		0.720 GeneticVariation disease GWASCAT Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate. 28054174 2017
Entrez Id: 8626
Gene Symbol: TP63
TP63 		0.720 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 8626
Gene Symbol: TP63
TP63 		0.720 Biomarker disease CTD_human Genotype-phenotype correlations in mapped split hand foot malformation (SHFM) patients. 16688749 2006
Entrez Id: 8626
Gene Symbol: TP63
TP63 		0.720 SusceptibilityMutation disease ORPHANET Mutation in SAM domain of TP63 is associated with nonsyndromic cleft lip and palate and cleft palate. 21567929 2011
Entrez Id: 27324
Gene Symbol: TOX3
TOX3 		0.010 GeneticVariation disease BEFREE Two novel genes TOX3 and COL21A1 in large extended Malay families with nonsyndromic cleft lip and/or palate. 30924295 2019
Entrez Id: 55266
Gene Symbol: TMEM19
TMEM19 		0.100 GeneticVariation disease GWASCAT Genome-wide analyses of non-syndromic cleft lip with palate identify 14 novel loci and genetic heterogeneity. 28232668 2017
Entrez Id: 255104
Gene Symbol: TMCO4
TMCO4 		0.100 GeneticVariation disease GWASCAT Genome-wide analyses of non-syndromic cleft lip with palate identify 14 novel loci and genetic heterogeneity. 28232668 2017
Entrez Id: 54499
Gene Symbol: TMCO1
TMCO1 		0.100 GeneticVariation disease CLINVAR
Entrez Id: 54499
Gene Symbol: TMCO1
TMCO1 		0.100 Biomarker disease HPO
Entrez Id: 7067
Gene Symbol: THRA
THRA 		0.010 Biomarker disease BEFREE We detected significant interaction between maternal smoking and the transmission of alleles for markers near TGFA and TGFB3; excess transmission of allele 3 at BCL3 was most significant among cleft lip probands; and the odds ratios for transmission of alleles at D19S178 and THRA1 were significant when ethnic group was included in the model. 9415696 1997
Entrez Id: 7055
Gene Symbol: THAS
THAS 		0.300 Biomarker disease CTD_human X-linked midline defects. 4039891 1985
Entrez Id: 63892
Gene Symbol: THADA
THADA 		0.100 GeneticVariation disease GWASCAT Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate. 20023658 2010
Entrez Id: 63892
Gene Symbol: THADA
THADA 		0.100 GeneticVariation disease GWASDB Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate. 20023658 2010
Entrez Id: 63892
Gene Symbol: THADA
THADA 		0.100 GeneticVariation disease GWASDB Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. 22863734 2012
Entrez Id: 7043
Gene Symbol: TGFB3
TGFB3 		0.050 GeneticVariation disease BEFREE We detected significant interaction between maternal smoking and the transmission of alleles for markers near TGFA and TGFB3; excess transmission of allele 3 at BCL3 was most significant among cleft lip probands; and the odds ratios for transmission of alleles at D19S178 and THRA1 were significant when ethnic group was included in the model. 9415696 1997