| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.400 | GeneticVariation | group | BEFREE | RNAse A mismatch cleavage analysis of 66 primary human colon tumors reveals a high incidence of K-ras genes with mutations at position 12. | 2438556 | 1987 | ||||
|
0.400 | Biomarker | group | CTD_human | Comet fluorescence in situ hybridization analysis for oxidative stress-induced DNA damage in colon cancer relevant genes. | 17192441 | 2007 | ||||
|
0.400 | Biomarker | group | CTD_human | ras p21 Isoprenylation inhibition induces flat colon tumors in Wistar rats. | 10813127 | 2000 | ||||
|
0.400 | Biomarker | group | CTD_human | Ursodeoxycholic acid inhibits Ras mutations, wild-type Ras activation, and cyclooxygenase-2 expression in colon cancer. | 12839936 | 2003 | ||||
|
0.400 | Biomarker | group | CTD_human | In the context of an Apc-mutant colonic tumor, activation of K-Ras led to defects in terminal differentiation and expansion of putative stem cells within the tumor epithelium. | 18372904 | 2008 | ||||
|
0.400 | Biomarker | group | CTD_human | Expression profiling of CC531 colon carcinoma cells reveals similar regulation of beta-catenin target genes by both butyrate and aspirin. | 12800193 | 2003 | ||||
|
0.400 | Biomarker | group | CTD_human | Isolation of a chemical inhibitor against K-Ras-induced p53 suppression through natural compound screening. | 19424582 | 2009 | ||||
|
0.400 | GeneticVariation | group | LHGDN | Mutations in the RAS-MAPK, PI(3)K (phosphatidylinositol-3-OH kinase) signaling network correlate with poor survival in a population-based series of colon cancers. | 18224685 | 2008 | ||||
|
0.400 | GeneticVariation | group | LHGDN | Polymorphisms in insulin-related genes predispose to specific KRAS2 and TP53 mutations in colon cancer. | 16448675 | 2006 | ||||
|
0.400 | Biomarker | group | LHGDN | p38 MAPK activation selectively induces cell death in K-ras-mutated human colon cancer cells through regulation of vitamin D receptor. | 15037631 | 2004 |