×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
0.490
CausalMutation
group
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
0.490
GeneticVariation
group
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
0.490
CausalMutation
group
CLINVAR
Prospective enterprise-level molecular genotyping of a cohort of cancer patients.
25157968
2014
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
0.490
GeneticVariation
group
CLINVAR
Prospective enterprise-level molecular genotyping of a cohort of cancer patients.
25157968
2014
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
0.490
CausalMutation
group
CLINVAR
Regorafenib in metastatic colorectal cancer.
24559322
2014
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
0.490
CausalMutation
group
CLINVAR
Prognostic role of PIK3CA mutation in colorectal cancer: cohort study and literature review.
22357840
2012
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
0.490
CausalMutation
group
CLINVAR
Phosphatidylinositide-3-kinase inhibitors: addressing questions of isoform selectivity and pharmacodynamic/predictive biomarkers in early clinical trials.
22162582
2012
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
0.490
CausalMutation
group
CLINVAR
Phase I, dose-escalation study of BKM120, an oral pan-Class I PI3K inhibitor, in patients with advanced solid tumors.
22162589
2012
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
0.490
CausalMutation
group
CLINVAR
Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis.
20619739
2010
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
0.490
CausalMutation
group
CLINVAR
Predictive biomarkers of sensitivity to the phosphatidylinositol 3' kinase inhibitor GDC-0941 in breast cancer preclinical models.
20453058
2010
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
0.490
GeneticVariation
group
CLINVAR
PIK3CA mutations are not a major determinant of resistance to the epidermal growth factor receptor inhibitor cetuximab in metastatic colorectal cancer.
19366826
2009
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
0.490
CausalMutation
group
CLINVAR
PIK3CA mutations predict local recurrences in rectal cancer patients.
19903786
2009
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
0.490
CausalMutation
group
CLINVAR
PIK3CA mutations are not a major determinant of resistance to the epidermal growth factor receptor inhibitor cetuximab in metastatic colorectal cancer.
19366826
2009
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
0.490
CausalMutation
group
CLINVAR
PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies.
19223544
2009
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
0.490
CausalMutation
group
CLINVAR
Breast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signaling.
18725974
2008
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
0.490
GeneticVariation
group
CLINVAR
Functional analysis of PIK3CA gene mutations in human colorectal cancer.
15930273
2005
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
0.490
CausalMutation
group
CLINVAR
Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic.
15647370
2005
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
0.490
CausalMutation
group
CLINVAR
The PIK3CA gene is mutated with high frequency in human breast cancers.
15254419
2004
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
0.490
CausalMutation
group
CLINVAR
High frequency of mutations of the PIK3CA gene in human cancers.
15016963
2004