Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1 		0.010 AlteredExpression group LHGDN Genetic variation in genes for the xenobiotic-metabolizing enzymes CYP1A1, EPHX1, GSTM1, GSTT1, and GSTP1 and susceptibility to colorectal cancer in Lynch syndrome. 18768509 2008
Entrez Id: 4629
Gene Symbol: MYH11
MYH11 		0.010 GeneticVariation group LHGDN Smooth-muscle myosin mutations in hereditary non-polyposis colorectal cancer syndrome. 18941465 2008
Entrez Id: 1312
Gene Symbol: COMT
COMT 		0.010 GeneticVariation group LHGDN Cytochrome P450 17A1 and catechol O-methyltransferase polymorphisms and age at Lynch syndrome colon cancer onset in Newfoundland. 17606708 2007
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.010 GeneticVariation group LHGDN The additive effect of p53 Arg72Pro and RNASEL Arg462Gln genotypes on age of disease onset in Lynch syndrome patients with pathogenic germline mutations in MSH2 or MLH1. 17224235 2007
Entrez Id: 768
Gene Symbol: CA9
CA9 		0.010 AlteredExpression group LHGDN Carbonic anhydrase IX is highly expressed in hereditary nonpolyposis colorectal cancer. 17855694 2007
Entrez Id: 6790
Gene Symbol: AURKA
AURKA 		0.010 GeneticVariation group LHGDN Association between Aurora-A kinase polymorphisms and age of onset of hereditary nonpolyposis colorectal cancer in a Caucasian population. 17219423 2007
Entrez Id: 1586
Gene Symbol: CYP17A1
CYP17A1 		0.010 GeneticVariation group LHGDN Cytochrome P450 17A1 and catechol O-methyltransferase polymorphisms and age at Lynch syndrome colon cancer onset in Newfoundland. 17606708 2007
Entrez Id: 6041
Gene Symbol: RNASEL
RNASEL 		0.010 GeneticVariation group LHGDN The additive effect of p53 Arg72Pro and RNASEL Arg462Gln genotypes on age of disease onset in Lynch syndrome patients with pathogenic germline mutations in MSH2 or MLH1. 17224235 2007
Entrez Id: 4582
Gene Symbol: MUC1
MUC1 		0.010 Biomarker group LHGDN Inverse effects of mucin on survival of matched hereditary nonpolyposis colorectal cancer and sporadic colorectal cancer patients. 16857798 2006
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		0.010 GeneticVariation group LHGDN BRAF-V600E is not involved in the colorectal tumorigenesis of HNPCC in patients with functional MLH1 and MSH2 genes. 15782118 2005
Entrez Id: 834
Gene Symbol: CASP1
CASP1 		0.010 GeneticVariation group LHGDN Differential rates of frameshift alterations in four repeat sequences of hereditary nonpolyposis colorectal cancer tumors. 12215842 2002
Entrez Id: 351
Gene Symbol: APP
APP 		0.010 GeneticVariation group LHGDN Differential rates of frameshift alterations in four repeat sequences of hereditary nonpolyposis colorectal cancer tumors. 12215842 2002
Entrez Id: 581
Gene Symbol: BAX
BAX 		0.010 GeneticVariation group LHGDN Differential rates of frameshift alterations in four repeat sequences of hereditary nonpolyposis colorectal cancer tumors. 12215842 2002
Entrez Id: 80204
Gene Symbol: FBXO11
FBXO11 		0.100 CausalMutation group CLINVAR Expanding the genotype-phenotype spectrum in hereditary colorectal cancer by gene panel testing. 27696107 2017
Entrez Id: 80204
Gene Symbol: FBXO11
FBXO11 		0.100 CausalMutation group CLINVAR Atypical dermal melanocytosis: a diagnostic clue in constitutional mismatch repair deficiency syndrome. 28369758 2017
Entrez Id: 80204
Gene Symbol: FBXO11
FBXO11 		0.100 GeneticVariation group CLINVAR Multigene Panel Testing Provides a New Perspective on Lynch Syndrome. 28514183 2017
Entrez Id: 80204
Gene Symbol: FBXO11
FBXO11 		0.100 CausalMutation group CLINVAR Use of multigene-panel identifies pathogenic variants in several CRC-predisposing genes in patients previously tested for Lynch Syndrome. 28195393 2017
Entrez Id: 80204
Gene Symbol: FBXO11
FBXO11 		0.100 GeneticVariation group CLINVAR Suspected Lynch syndrome associated MSH6 variants: A functional assay to determine their pathogenicity. 28531214 2017
Entrez Id: 80204
Gene Symbol: FBXO11
FBXO11 		0.100 GeneticVariation group CLINVAR Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients With Early-Onset Colorectal Cancer. 27978560 2017
Entrez Id: 80204
Gene Symbol: FBXO11
FBXO11 		0.100 GeneticVariation group CLINVAR Targeted sequencing of 36 known or putative colorectal cancer susceptibility genes. 28944238 2017
Entrez Id: 80204
Gene Symbol: FBXO11
FBXO11 		0.100 CausalMutation group CLINVAR Gene panel sequencing in familial breast/ovarian cancer patients identifies multiple novel mutations also in genes others than BRCA1/2. 27616075 2017
Entrez Id: 80204
Gene Symbol: FBXO11
FBXO11 		0.100 GeneticVariation group CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312 2016
Entrez Id: 80204
Gene Symbol: FBXO11
FBXO11 		0.100 CausalMutation group CLINVAR Improving performance of multigene panels for genomic analysis of cancer predisposition. 26845104 2016
Entrez Id: 80204
Gene Symbol: FBXO11
FBXO11 		0.100 CausalMutation group CLINVAR Screening for germline mutations in breast/ovarian cancer susceptibility genes in high-risk families in Israel. 26687385 2016
Entrez Id: 80204
Gene Symbol: FBXO11
FBXO11 		0.100 CausalMutation group CLINVAR Prevalence of Pathogenic Mutations in Cancer Predisposition Genes among Pancreatic Cancer Patients. 26483394 2016