Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 Biomarker disease BEFREE We examined the association of circulating ApoE with cardiovascular risk factors in the two population-based studies (ELSA and NPHSII) and the relationship between ApoE concentration and coronary heart disease and stroke in all three studies. 27755538 2016
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 Biomarker disease BEFREE APOE ε2 represents the first significant association for multiple subclinical atherosclerosis traits across multiple ethnicities, as well as clinical coronary heart disease. 27872105 2016
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 GeneticVariation disease BEFREE Common variants of apolipoprotein E and cholesteryl ester transport protein genes in male patients with coronary heart disease and variable body mass index. 24402318 2015
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 GeneticVariation disease BEFREE APOE genotype was included as a positive control for risk of ischaemic heart disease. 25981321 2015
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 GeneticVariation disease BEFREE Significant interaction of APOE rs4420638 polymorphism with HDL-C and APOA-I levels in coronary heart disease in Han Chinese men. 26535656 2015
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 Biomarker disease BEFREE Meta-analysis for the Association of Apolipoprotein E ε2/ε3/ε4 Polymorphism with Coronary Heart Disease. 25963363 2015
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 Biomarker disease BEFREE Secretoneurin gene therapy improves hind limb and cardiac ischaemia in Apo E⁻/⁻ mice without influencing systemic atherosclerosis. 25377726 2015
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 GeneticVariation disease BEFREE Apolipoprotein E gene polymorphism and risk for coronary heart disease in the Chinese population: a meta-analysis of 61 studies including 6634 cases and 6393 controls. 24755673 2014
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 GeneticVariation disease BEFREE A systematic review and meta-analysis of 130,000 individuals shows smoking does not modify the association of APOE genotype on risk of coronary heart disease. 25173947 2014
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 GeneticVariation disease BEFREE Fatty acid metabolism in carriers of apolipoprotein E epsilon 4 allele: is it contributing to higher risk of cognitive decline and coronary heart disease? 25333200 2014
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 GeneticVariation disease BEFREE We investigated a possible interaction of apolipoprotein E (APOE) gene with birthplace on the risk of myocardial infarction (MI) and coronary atherosclerosis. 23110590 2013
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 GeneticVariation disease BEFREE Association between apolipoprotein E gene polymorphism and the risk of coronary artery disease in Chinese population: evidence from a meta-analysis of 40 studies. 23826174 2013
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 GeneticVariation disease BEFREE Interaction of apolipoprotein E genotype with smoking and physical inactivity on coronary heart disease risk in men and women. 22071360 2012
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 GeneticVariation disease BEFREE Apolipoprotein E gene polymorphism: effects on plasma lipids and risk of type 2 diabetes and coronary artery disease. 22520940 2012
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 GeneticVariation disease BEFREE In the present case-control study, we examined polymorphisms -427 T/C and -491 A/T in the promoter region of APOE in relation to lipid profile and the coronary atherosclerosis, in a sample of Argentinean adults with (cases) and without (controls) atherosclerotic injuries regarding gender and age. 22101914 2012
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 GeneticVariation disease BEFREE We therefore investigated whether the LDLR locus interacted with the apolipoprotein E gene genotype on coronary heart disease risk in patients clinically diagnosed with familial hypercholesterolemia with and without LDLR mutation. 22010136 2011
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 GeneticVariation disease BEFREE The ε4 allele of APOE gene was shown to be associated both with an increased risk for coronary heart disease and late-onset Alzheimer disease. 20543710 2011
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 GeneticVariation disease BEFREE The apolipoprotein E gene (APOE) coding polymorphism modifies the risks of Alzheimer's disease, type 2 diabetes, and coronary heart disease. 22028770 2011
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 GeneticVariation disease BEFREE Saturated fat intake and alcohol consumption modulate the association between the APOE polymorphism and risk of future coronary heart disease: a nested case-control study in the Spanish EPIC cohort. 20688498 2011
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 GeneticVariation disease BEFREE Effect of apolipoprotein E genotypes on incidence and development of coronary stenosis in Iranian patients with coronary artery disease. 21254242 2011
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 GeneticVariation disease BEFREE Atheromatosis extent in coronary artery disease is not correlated with apolipoprotein-E polymorphism and its plasma levels, but associated with cognitive decline. 20455863 2010
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 Biomarker disease BEFREE APOE/C1/C4/C2 gene cluster genotypes, haplotypes and lipid levels in prospective coronary heart disease risk among UK healthy men. 20498921 2010
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 GeneticVariation disease BEFREE Butyrylcholinesterase K variant and the APOE-epsilon 4 allele work in synergy to increase the risk of coronary artery disease especially in diabetic patients. 19685167 2010
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 GeneticVariation disease BEFREE Apolipoprotein E polymorphism and the characteristics of diseased vessels in male Chinese patients with angiographic coronary artery disease: a case-case study. 20552590 2010
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 GeneticVariation disease BEFREE Associations of lipoprotein lipase S447X and apolipoprotein E genotypes with low-density lipoprotein subfractions in Turkish patients with coronary artery disease. 19368142 2009