Gene: PTGS2 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.100 AlteredExpression disease BEFREE Predicting significance of COX-2 expression of peripheral blood monocyte in patients with coronary artery disease. 31700919 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.100 Biomarker disease BEFREE S100A8/A9 expression was significantly correlated with TLR-4 and COX-2 in the ACS group and with TLR-4 in the CHD group. 30367682 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.100 Biomarker disease BEFREE Also, it indicated that sodium/hydrogen exchanger 3 (SLC9A3), Prostaglandin G/H synthase 2 (PTGS2), Oxidized low-density lipoprotein receptor 1 (OLR1), and fibrinogen gamma chain (FGG) may be potential therapeutic targets for CHD. 28629174 2017
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.100 GeneticVariation disease BEFREE The COX-2 rs20417 polymorphism and risk of coronary artery disease: evidence from 17,621 subjects. 24513487 2014
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.100 GeneticVariation disease BEFREE PTGS2 gene polymorphism -765G>C is associated with coronary artery disease: a meta-analysis. 24446343 2014
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.100 Biomarker disease BEFREE We showed that COX-2 is expressed in diseased lung tissue, indicating a relationship between COX-2 and vascular remodeling in pulmonary arteries in CHD. 23681850 2013
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.100 GeneticVariation disease BEFREE Interaction between COX-2 G-765C and smoking in relation to coronary artery disease in a Chinese Uighur population. 21091235 2011
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.100 GeneticVariation disease BEFREE Cox-2 gene polymorphism and IL-6 levels in coronary artery disease. 21574137 2011
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.100 GeneticVariation disease BEFREE Functional promoter polymorphism of cyclooxygenase-2 modulates the inflammatory response in stable coronary heart disease. 20332714 2010
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.100 GeneticVariation disease BEFREE Cyclooxygenase-2 (COX-2) G-765C is a protective factor for coronary artery disease but not for ischemic stroke: a meta-analysis. 19631939 2009
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.100 GeneticVariation disease BEFREE A secondary aim was to replicate the interaction of PTGS2 rs20417 (-765G to C) with aspirin use on coronary heart disease risk observed in the Atherosclerosis Risk in Communities Study (ARIC). 19046748 2009
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.100 GeneticVariation disease BEFREE However, aspirin utilization appeared to modify the relationship between the PTGS2 G-765C polymorphism and CHD risk (interaction P=0.072). 17495879 2008
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.100 GeneticVariation disease BEFREE COX-2 gene promoter polymorphism and coronary artery disease in middle-aged men: the Helsinki sudden death study. 18385811 2008
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.100 GeneticVariation disease BEFREE The COX-2 G-765C polymorphism was not a significant predictor of CHD in either racial group, but it was a significant predictor of incident stroke in African-Americans. 17350020 2008
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.100 GeneticVariation disease BEFREE Common polymorphisms of cyclooxygenase-2 and prostaglandin E2 receptor and increased risk for acute coronary syndrome in coronary artery disease. 18989535 2008