Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1969
Gene Symbol: EPHA2
EPHA2 		0.010 Biomarker disease BEFREE EphA2/ephrinA1 staining activities in adenoid cystic carcinoma were more significant than those in normal gland tissue (P < .01). 23298804 2013
Entrez Id: 406954
Gene Symbol: MIR181A2
MIR181A2 		0.010 Biomarker disease BEFREE MicroRNA-181a suppresses salivary adenoid cystic carcinoma metastasis by targeting MAPK-Snai2 pathway. 23911747 2013
Entrez Id: 358
Gene Symbol: AQP1
AQP1 		0.310 Biomarker disease BEFREE Aquaporin-1 (AQP1) is a candidate oncogene that is epigenetically modified in adenoid cystic carcinoma (ACC). 24493792 2014
Entrez Id: 84182
Gene Symbol: MINDY4
MINDY4 		0.010 Biomarker disease BEFREE Aquaporin-1 (AQP1) is a candidate oncogene that is epigenetically modified in adenoid cystic carcinoma (ACC). 24493792 2014
Entrez Id: 6899
Gene Symbol: TBX1
TBX1 		0.020 Biomarker disease BEFREE Brachyury was knocked down by transfecting Brachyury short hairpin RNA (shRNA) into the AdCC CSC cell line ACCS-M GFP. 24504414 2014
Entrez Id: 5036
Gene Symbol: PA2G4
PA2G4 		0.010 Biomarker disease BEFREE ErbB3 binding protein 1 (EBP1) has been recently reported to function as a tumor suppressor in the progression of multiple cancers, including breast cancer, prostate cancer, salivary adenoid cystic carcinoma (ACC), and oral squamous cell carcinoma (OSCC). 25081333 2014
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4 		0.050 Biomarker disease BEFREE CXCR4 antagonist inhibits perineural invasion of adenoid cystic carcinoma. 25118295 2014
Entrez Id: 214
Gene Symbol: ALCAM
ALCAM 		0.010 Biomarker disease BEFREE CD166 immunoreactivity in malignant tumors (adenoid cystic carcinoma (ACC) and mucoepidermoid carcinoma (MEC)) (56.7 ± 14.05) was significantly higher than that of pleomorphic adenoma (PA) (34.3 ± 17.07) (P < 0.000) and higher in the PA than normal salivary gland (13.2 ± 12.1) (P = 0.001). 25472586 2015
Entrez Id: 346389
Gene Symbol: MACC1
MACC1 		0.010 AlteredExpression disease BEFREE Metastasis-associated in colon cancer-1 expression was analysed in 65 paraffin-embedded tissue specimens of salivary adenoid cystic carcinoma and 25 adjacent non-cancerous tissues by immunohistochemistry (IHC). 25640194 2015
Entrez Id: 2535
Gene Symbol: FZD2
FZD2 		0.010 Biomarker disease BEFREE FZD2 inhibits the cell growth and migration of salivary adenoid cystic carcinomas. 25695658 2016
Entrez Id: 57509
Gene Symbol: MTUS1
MTUS1 		0.010 AlteredExpression disease BEFREE MTUS1/ATIP3a down-regulation is associated with enhanced migration, invasion and poor prognosis in salivary adenoid cystic carcinoma. 25885343 2015
Entrez Id: 407037
Gene Symbol: MIR320A
MIR320A 		0.010 Biomarker disease BEFREE MiR-320a acts as a prognostic factor and Inhibits metastasis of salivary adenoid cystic carcinoma by targeting ITGB3. 25924850 2015
Entrez Id: 4602
Gene Symbol: MYB
MYB 		0.400 Biomarker disease BEFREE MYB rearrangement and clinicopathologic characteristics in head and neck adenoid cystic carcinoma. 25963073 2015
Entrez Id: 10879
Gene Symbol: SMR3B
SMR3B 		0.010 Biomarker disease BEFREE PRL-3 promotes migration and invasion and is associated with poor prognosis in salivary adenoid cystic carcinoma. 26041460 2016
Entrez Id: 11156
Gene Symbol: PTP4A3
PTP4A3 		0.010 Biomarker disease BEFREE PRL-3 promotes migration and invasion and is associated with poor prognosis in salivary adenoid cystic carcinoma. 26041460 2016
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.040 Biomarker disease BEFREE VEGF and Ki-67 Overexpression in Predicting Poor Overall Survival in Adenoid Cystic Carcinoma. 26194375 2016
Entrez Id: 7295
Gene Symbol: TXN
TXN 		0.010 Biomarker disease BEFREE Thioredoxin 1 mediates TGF-β-induced epithelial-mesenchymal transition in salivary adenoid cystic carcinoma. 26325518 2015
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1 		0.010 AlteredExpression disease BEFREE DNMT1 mRNA expression in ACC-M after treatment with GAA for 72 h was lower than that in control cells (P < 0.05). 26535659 2015
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1 		0.440 Biomarker disease BEFREE NOTCH1 and SOX10 are Essential for Proliferation and Radiation Resistance of Cancer Stem-Like Cells in Adenoid Cystic Carcinoma. 27084744 2016
Entrez Id: 4602
Gene Symbol: MYB
MYB 		0.400 Biomarker disease BEFREE MYB and c-KIT (CD117) were negative, thereby strongly arguing against the diagnosis of adenoid cystic carcinoma. 27567603 2017
Entrez Id: 4781
Gene Symbol: NFIB
NFIB 		0.400 GeneticVariation disease BEFREE NFIB-associated gene rearrangement is a frequent genetic event in vulvar adenoid cystic carcinomas. 27662035 2017
Entrez Id: 3861
Gene Symbol: KRT14
KRT14 		0.020 AlteredExpression disease BEFREE CK14 expression in the invasive front, local regional recurrence and distant metastasis were independent and significant prognostic factors in SACC patients. 28152077 2017
Entrez Id: 6663
Gene Symbol: SOX10
SOX10 		0.060 Biomarker disease BEFREE SOX10 showed positivity in spiradenomas (13/13), cylindromas (9/10), hidradenoma papilliferum (10/10), syringocystadenoma papilliferum (8/10), apocrine adenomas (8/10), and negativity in poromas (0/12), syringomas (0/10), and basal cell carcinomas (0/13). 28343365 2017
Entrez Id: 6663
Gene Symbol: SOX10
SOX10 		0.060 AlteredExpression disease BEFREE Sox10 was expressed in 100% of cylindromas and spiradenomas, and in variable frequency in other benign and malignant tumors of sweat glands. 28394798 2017
Entrez Id: 55107
Gene Symbol: ANO1
ANO1 		0.020 Biomarker disease BEFREE DOG1 was positive in most cylindromas (87.5%), in only 10.5% of spiradenomas, and was variably expressed in other benign and malignant tumors of sweat glands. 28394798 2017