Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
0.320 Biomarker disease CTD_human The CYP2D6B allele is associated with a milder synaptic pathology in Alzheimer's disease. 7574463 1995
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
0.320 GeneticVariation disease BEFREE There was no relationship between CYP2D6 alleles and the age of onset and advancement of dementia in AD and PD. 17530572 2007
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
0.320 GeneticVariation disease BEFREE In addition, about 10-20% of Caucasians are carriers of defective CYP2D6 polymorphic variants that alter the metabolism and effects of AD drugs and many psychotropic agents currently administered to patients with dementia. 18322383 2008