Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.580 | Biomarker | group | BEFREE | Myelin basic protein (MBP) is a major component of the myelin sheath of CNS neurons and may play a central role in demyelinating diseases such as MS. | 28413712 | 2017 | ||||
|
0.580 | Biomarker | group | BEFREE | MBP is an abundant myelin protein involved in demyelinating diseases, such as multiple sclerosis. | 28694532 | 2017 | ||||
|
0.580 | Biomarker | group | BEFREE | Alterations of the balance between MBP-specific proliferation and PCD are present in demyelinating diseases and could play a major role in the pathogenesis of these diseases. | 18930441 | 2008 | ||||
|
0.580 | Biomarker | group | BEFREE | Myelin basic protein (MBP) is required for normal myelin compaction and is implicated in both experimental and human demyelinating diseases. | 14614079 | 2003 | ||||
|
0.580 | Biomarker | group | RGD | Insertion of a retrotransposon in Mbp disrupts mRNA splicing and myelination in a new mutant rat. | 10212300 | 1999 | ||||
|
0.580 | Biomarker | group | BEFREE | These findings are also evidence for limited usage of V-region Ig genes in the immune response of humans to MBP and the possible importance of an Id network for MBP in demyelinating disease. | 9484364 | 1998 | ||||
|
0.580 | Biomarker | group | BEFREE | Myelin basic protein in experimental allergic encephalomyelitis is not affected at the posttranslational level: implications for demyelinating disease. | 8739153 | 1996 | ||||
|
0.580 | GeneticVariation | group | BEFREE | Recombinant vaccinia viruses encoding an encephalitogenic portion of myelin basic protein (MBP) were evaluated in an animal model for human demyelinating disease, experimental allergic encephalomyelitis (EAE). | 8632058 | 1996 | ||||
|
0.580 | Biomarker | group | BEFREE | Experimental allergic encephalomyelitis (EAE) is a T cell mediated model of demyelinating disease that develops as a result of an autoimmune response to the myelin structural antigen, myelin basic protein (MBP). | 1718484 | 1991 | ||||
|
0.580 | Biomarker | group | CTD_human | High-dose methotrexate-induced neurotoxicity associated with elevation of CSF myelin basic protein. | 2580064 | 1985 |