Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3240
Gene Symbol: HP
HP
0.360 GeneticVariation disease BEFREE Preliminary data suggest the possibility of linkage between the alpha-haptoglobin locus and third component of complement locus and depression spectrum disease, a depression which is familially defined by the presence of alcoholism in the first-degree family member. 401356 1979
Entrez Id: 3240
Gene Symbol: HP
HP
0.360 Biomarker disease BEFREE The results show virtually no evidence of linkage between depression spectrum disease and C3, but suggestive evidence (lod score = 1.03) of linkage between depression spectrum disease and alpha-haptoglobin (both these linkages were previously suggested by significant results in sib-pair analyses). 431798 1979
Entrez Id: 100379198
Gene Symbol: ECT
ECT
0.100 Biomarker disease BEFREE The presence of a family history of depression may be predictive to some extent of a good response to adequate tricyclic medication or ECT. 453352 1979
Entrez Id: 6046
Gene Symbol: BRD2
BRD2
0.020 Biomarker disease BEFREE Save for a depression in plasma FSH in the early follicular phase, this hormone, as wells as LH and progesterone patterns in our patient, were similar to the comparison cohorts. 498052 1979
Entrez Id: 3240
Gene Symbol: HP
HP
0.360 Biomarker disease BEFREE Preliminary data indicate that depression spectrum disease may be linked to such genetic markers as C3 or alpha-haptoglobin. 760696 1979
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
0.320 Biomarker disease PSYGENET Interictal behavioral disturbances: a search for molecular substrates. 1337448 1992
Entrez Id: 847
Gene Symbol: CAT
CAT
0.100 AlteredExpression disease BEFREE Depression of catalase gene expression in the liver of tumor bearing nude mice. 1472018 1992
Entrez Id: 1392
Gene Symbol: CRH
CRH
0.600 Biomarker disease BEFREE CRF overproduction has been implicated in affective disorders, such as depression and anorexia nervosa, and may lead to Cushing's syndrome. 1597149 1992
Entrez Id: 10882
Gene Symbol: C1QL1
C1QL1
0.040 Biomarker disease BEFREE CRF overproduction has been implicated in affective disorders, such as depression and anorexia nervosa, and may lead to Cushing's syndrome. 1597149 1992
Entrez Id: 3688
Gene Symbol: ITGB1
ITGB1
0.010 Biomarker disease BEFREE CIAA+ICA+ first-degree relatives of individuals with type I diabetes have increased numbers of CD4 cells bearing the CD45R antigen and reciprocal depressions of the CD4 cells bearing the CD29 determinant. 1827080 1991
Entrez Id: 5788
Gene Symbol: PTPRC
PTPRC
0.010 Biomarker disease BEFREE CIAA+ICA+ first-degree relatives of individuals with type I diabetes have increased numbers of CD4 cells bearing the CD45R antigen and reciprocal depressions of the CD4 cells bearing the CD29 determinant. 1827080 1991
Entrez Id: 2152
Gene Symbol: F3
F3
0.010 AlteredExpression disease BEFREE There was a significant depression (66%) of the induced level of TF mRNA expression in response to lipopolysaccharide. 2293902 1990
Entrez Id: 353
Gene Symbol: APRT
APRT
0.330 Biomarker disease PSYGENET Similar studies with somatic cell mutants deficient in some component of cyclic AMP action or metabolism indicated that the depression in purine synthetic rates required G1 arrest and did not result from cell death. 2414305 1985
Entrez Id: 2
Gene Symbol: A2M
A2M
0.300 Biomarker disease PSYGENET CF heterozygotes shared the decrease of alpha 1-lipoprotein with the patients while exhibiting small but significant depressions of alpha 2-macroglobulin and IgG. 2432615 1987
Entrez Id: 28954
Gene Symbol: REM1
REM1
0.100 Biomarker disease BEFREE Siblings with non-reduced REM latency had a higher rate of depression (36.8%) than non-reduced REM latency parents (0.0%). 2521654 1989
Entrez Id: 7200
Gene Symbol: TRH
TRH
0.340 Biomarker disease BEFREE The results of the TRH test and the DST point to similar endocrinological patterns in alcoholics as in depressive patients and thus support the hypothesis of a link between alcoholism and depression. 2543997 1989
Entrez Id: 7200
Gene Symbol: TRH
TRH
0.340 Biomarker disease PSYGENET The results of the TRH test and the DST point to similar endocrinological patterns in alcoholics as in depressive patients and thus support the hypothesis of a link between alcoholism and depression. 2543997 1989
Entrez Id: 667
Gene Symbol: DST
DST
0.050 Biomarker disease BEFREE The results of the TRH test and the DST point to similar endocrinological patterns in alcoholics as in depressive patients and thus support the hypothesis of a link between alcoholism and depression. 2543997 1989
Entrez Id: 3855
Gene Symbol: KRT7
KRT7
0.100 GeneticVariation disease BEFREE Forty-three subjects (77%) evidenced mild depression of which 13 (23%) reported moderate-severe symptoms by the Beck Depression Inventory--a finding confirmed with Hamilton Rating Scale for Depression and the SCL-90-D scale. 2934456 1985
Entrez Id: 6886
Gene Symbol: TAL1
TAL1
0.100 GeneticVariation disease BEFREE Forty-three subjects (77%) evidenced mild depression of which 13 (23%) reported moderate-severe symptoms by the Beck Depression Inventory--a finding confirmed with Hamilton Rating Scale for Depression and the SCL-90-D scale. 2934456 1985
Entrez Id: 51540
Gene Symbol: SCLY
SCLY
0.100 GeneticVariation disease BEFREE Forty-three subjects (77%) evidenced mild depression of which 13 (23%) reported moderate-severe symptoms by the Beck Depression Inventory--a finding confirmed with Hamilton Rating Scale for Depression and the SCL-90-D scale. 2934456 1985
Entrez Id: 2996
Gene Symbol: GYPE
GYPE
0.310 Biomarker disease BEFREE Indications of linkage between familial pure depressive disease and MNS and depression spectrum disease and ORM were found, as had been previously suggested. 3233232 1988
Entrez Id: 2996
Gene Symbol: GYPE
GYPE
0.310 Biomarker disease PSYGENET Indications of linkage between familial pure depressive disease and MNS and depression spectrum disease and ORM were found, as had been previously suggested. 3233232 1988
Entrez Id: 2993
Gene Symbol: GYPA
GYPA
0.020 Biomarker disease BEFREE Indications of linkage between familial pure depressive disease and MNS and depression spectrum disease and ORM were found, as had been previously suggested. 3233232 1988
Entrez Id: 2316
Gene Symbol: FLNA
FLNA
0.020 Biomarker disease BEFREE Indications of linkage between familial pure depressive disease and MNS and depression spectrum disease and ORM were found, as had been previously suggested. 3233232 1988