Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.330 | Biomarker | disease | PSYGENET | Our data suggest that the 5-HT4 receptor is involved in the neurobiological mechanism underlying familial risk for depression, and that lower striatal 5-HT4 receptor binding is associated with increased risk for developing MDD. | 25522384 | 2014 | ||||
|
0.330 | Biomarker | disease | BEFREE | Our data suggest that the 5-HT4 receptor is involved in the neurobiological mechanism underlying familial risk for depression, and that lower striatal 5-HT4 receptor binding is associated with increased risk for developing MDD. | 25522384 | 2014 | ||||
|
0.330 | Biomarker | disease | BEFREE | Our findings suggested that p11 might be a potential regulator on 5-HTR1b and 5-HTR4 as well as a predictor of or a therapeutic target for IFN-α-induced depression. | 26821757 | 2016 | ||||
|
0.330 | Biomarker | disease | PSYGENET | Reversal of depressed behaviors in mice by p11 gene therapy in the nucleus accumbens. | 20962330 | 2010 | ||||
|
0.330 | Biomarker | disease | BEFREE | These findings are a translation of the memory enhancing effects of 5-HT4 receptor agonism seen in animal studies, and lend weight to the idea that the 5-HT4 receptor could be an innovative target for the treatment of cognitive deficits associated with depression and other neuropsychiatric disorders. | 31615585 | 2019 | ||||
|
0.330 | Biomarker | disease | PSYGENET | This study investigated differences in 5-HT(4) receptor and 5-HT transporter (5-HTT) binding by quantitative autoradiography of [(3)H]SB207145 and (S)-[N-methyl-(3)H]citalopram in two murine models of depression-related states, olfactory bulbectomy and glucocorticoid receptor heterozygous (GR(+/-)) mice. | 20060867 | 2010 | ||||
|
0.330 | Biomarker | disease | PSYGENET | Thus, the 5-HT(4) receptor binding was decreased in the Flinders Sensitive Line depression model and in response to chronic paroxetine administration. | 19476548 | 2009 |