Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1816
Gene Symbol: DRD5
DRD5
0.300 Biomarker disease CTD_human Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium. 14708030 2004
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.300 Biomarker disease CTD_human Increased expression of the Vesicular Glutamate Transporter-1 (VGLUT1) in the prefrontal cortex correlates with differential vulnerability to chronic stress in various mouse strains: effects of fluoxetine and MK-801. 21945287 2012
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.300 Biomarker disease CTD_human Functional polymorphisms in the interleukin-6 and serotonin transporter genes, and depression and fatigue induced by interferon-alpha and ribavirin treatment. 18458677 2009
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2
0.300 Biomarker disease CTD_human Paroxetine for prevention of depressive symptoms induced by interferon-alpha and ribavirin for hepatitis C. 17451562 2007
Entrez Id: 51738
Gene Symbol: GHRL
GHRL
0.300 Biomarker disease CTD_human Ghrelin, paraoxonase and arylesterase levels in depressive patients before and after citalopram treatment. 19272368 2009
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
0.300 Biomarker disease CTD_human Methylenetetrahydrofolate reductase (MTHFR) genetic polymorphisms and psychiatric disorders: a HuGE review. 17074966 2007
Entrez Id: 1269
Gene Symbol: CNR2
CNR2
0.300 Biomarker disease CTD_human Brain neuronal CB2 cannabinoid receptors in drug abuse and depression: from mice to human subjects. 18286196 2008
Entrez Id: 1387
Gene Symbol: CREBBP
CREBBP
0.300 Biomarker disease PSYGENET Gene expression in patients with endogenous depression was similar to that in the normal controls, except for upregulation of five genes (APP, CREBBP, GNAS, PDCD2 and PDCD6). 19955554 2010
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.300 Biomarker disease CTD_human Repeated electroconvulsive stimuli increase brain-derived neurotrophic factor in ACTH-treated rats. 16330021 2006
Entrez Id: 4282
Gene Symbol: MIF
MIF
0.300 Biomarker disease CTD_human Macrophage migration inhibitory factor is critically involved in basal and fluoxetine-stimulated adult hippocampal cell proliferation and in anxiety, depression, and memory-related behaviors. 20177408 2011
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
0.300 Biomarker disease CTD_human Lipid peroxidation and antioxidant protection in patients during acute depressive episodes and in remission after fluoxetine treatment. 19605942 2009
Entrez Id: 23705
Gene Symbol: CADM1
CADM1
0.300 Biomarker disease CTD_human Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains. 22113448 2012
Entrez Id: 351
Gene Symbol: APP
APP
0.300 Biomarker disease PSYGENET Gene expression in patients with endogenous depression was similar to that in the normal controls, except for upregulation of five genes (APP, CREBBP, GNAS, PDCD2 and PDCD6). 19955554 2010
Entrez Id: 3363
Gene Symbol: HTR7
HTR7
0.300 Biomarker disease CTD_human Optimization of (arylpiperazinylbutyl)oxindoles exhibiting selective 5-HT₇ receptor antagonist activity. 21859099 2011
Entrez Id: 2247
Gene Symbol: FGF2
FGF2
0.300 Biomarker disease CTD_human Hippocampal FGF-2 and FGFR1 mRNA expression in major depression, schizophrenia and bipolar disorder. 16861106 2006
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
0.300 Biomarker disease CTD_human A kinesin signaling complex mediates the ability of GSK-3beta to affect mood-associated behaviors. 20534517 2010
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2
0.300 Biomarker disease CTD_human Factors influencing long-term changes in mental health after interferon-alpha treatment of chronic hepatitis C. 19691667 2009
Entrez Id: 2495
Gene Symbol: FTH1
FTH1
0.300 Biomarker disease CTD_human The relationship between depression and serum ferritin level. 17063146 2007
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
0.300 Biomarker disease CTD_human Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances. 20357757 2010
Entrez Id: 85458
Gene Symbol: DIXDC1
DIXDC1
0.300 Biomarker disease CTD_human DIXDC1 contributes to psychiatric susceptibility by regulating dendritic spine and glutamatergic synapse density via GSK3 and Wnt/β-catenin signaling. 27752079 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.300 Biomarker disease CTD_human Chronic treatment with celecoxib reverses chronic unpredictable stress-induced depressive-like behavior via reducing cyclooxygenase-2 expression in rat brain. 19356723 2009
Entrez Id: 4852
Gene Symbol: NPY
NPY
0.300 Biomarker disease CTD_human Alterations in neuropeptide Y and Y1 receptor mRNA expression in brains from an animal model of depression: region specific adaptation after fluoxetine treatment. 9729278 1998
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
0.300 Biomarker disease CTD_human Regional serotonin transporter availability and depression are correlated in Wilson's disease. 12898347 2003
Entrez Id: 2778
Gene Symbol: GNAS
GNAS
0.300 Biomarker disease PSYGENET Gene expression in patients with endogenous depression was similar to that in the normal controls, except for upregulation of five genes (APP, CREBBP, GNAS, PDCD2 and PDCD6). 19955554 2010
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2
0.300 Biomarker disease CTD_human A randomized trial of paroxetine to prevent interferon-alpha-induced depression in patients with hepatitis C. 17292481 2007