Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2205
Gene Symbol: FCER1A
FCER1A 		0.300 Biomarker group CTD_human Genetic markers for differentiating aspirin-hypersensitivity. 16502481 2006
Entrez Id: 3119
Gene Symbol: HLA-DQB1
HLA-DQB1 		0.300 Biomarker group CTD_human Genetic markers for differentiating aspirin-hypersensitivity. 16502481 2006
Entrez Id: 3447
Gene Symbol: IFNA13
IFNA13 		0.010 Biomarker group BEFREE Here, we aimed to investigate the immunological mechanisms underlying pegylated IFN-α-induced drug eruptions. 25831972 2015
Entrez Id: 3439
Gene Symbol: IFNA1
IFNA1 		0.010 Biomarker group BEFREE Here, we aimed to investigate the immunological mechanisms underlying pegylated IFN-α-induced drug eruptions. 25831972 2015
Entrez Id: 3606
Gene Symbol: IL18
IL18 		0.300 Biomarker group CTD_human Neutrophil activation in patients with ASA-induced urticaria. 18204966 2008
Entrez Id: 4353
Gene Symbol: MPO
MPO 		0.300 Biomarker group CTD_human Neutrophil activation in patients with ASA-induced urticaria. 18204966 2008
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1 		0.020 GeneticVariation group BEFREE Our results show that GSTP1 polymorphism is not a significant contributor to drug eruption risk. 14740231 2004
Entrez Id: 406953
Gene Symbol: MIR18A
MIR18A 		0.010 AlteredExpression group BEFREE Serum miR-18a-5p levels can be a useful disease marker for drug eruptions. 24184144 2014
Entrez Id: 6361
Gene Symbol: CCL17
CCL17 		0.020 AlteredExpression group BEFREE Serum TARC levels are strongly correlated with blood eosinophil count in patients with drug eruptions. 27497618 2017
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1 		0.020 GeneticVariation group BEFREE The GSTM1 and GSTT1 gene polymorphisms seem to be associated with the development of drug eruption. 14740231 2004
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1 		0.020 GeneticVariation group LHGDN The GSTM1 and GSTT1 gene polymorphisms seem to be associated with the development of drug eruption. 14740231 2004
Entrez Id: 6361
Gene Symbol: CCL17
CCL17 		0.020 Biomarker group BEFREE The aim of this study was to test whether the thymus and activation-regulated chemokine (TARC) level in serum at an early stage of a drug eruption can serve as a prognostic biomarker of systemic inflammation. 28648978 2018
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1 		0.020 GeneticVariation group LHGDN The GSTM1 and GSTT1 gene polymorphisms seem to be associated with the development of drug eruption. 14740231 2004
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1 		0.020 GeneticVariation group BEFREE The GSTM1 and GSTT1 gene polymorphisms seem to be associated with the development of drug eruption. 14740231 2004
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1 		0.020 Biomarker group BEFREE The GSTP1 Val/Val genotype was significantly associated with non-photosensitive drug eruptions (OR = 3.64, P value = 0.038), whereas associations observed between GSTP1, GSTM1, GSTT1 polymorphisms and photosensitive drug eruptions did not reach statistical significance. 30737837 2019
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1 		0.020 GeneticVariation group BEFREE The GSTP1 Val/Val genotype was significantly associated with non-photosensitive drug eruptions (OR = 3.64, P value = 0.038), whereas associations observed between GSTP1, GSTM1, GSTT1 polymorphisms and photosensitive drug eruptions did not reach statistical significance. 30737837 2019
Entrez Id: 472
Gene Symbol: ATM
ATM 		0.010 Biomarker group BEFREE The measures for the drug profiles were medicine type (ATC-code), mono- and polypharmacy, CYP-enzyme metabolism pattern, and medicine with a potential to induce lichenoid drug eruptions. 12974517 2003
Entrez Id: 9360
Gene Symbol: PPIG
PPIG 		0.010 AlteredExpression group BEFREE The measures for the drug profiles were medicine type (ATC-code), mono- and polypharmacy, CYP-enzyme metabolism pattern, and medicine with a potential to induce lichenoid drug eruptions. 12974517 2003
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.310 Biomarker group BEFREE The present case indicates that tumor necrosis factor-α antagonist is a safe, fast and effective treatment for severe drug eruption, but it is unable to prevent the rise of peripheral blood eosinophils. 29285114 2017
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1 		0.020 GeneticVariation group BEFREE Variations in GSTP1 may affect the risk to develop non-photo-induced drug eruptions. 30737837 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.300 Biomarker group CTD_human Warfarin skin necrosis associated with protein S deficiency and a mutation in the methylenetetrahydrofolate reductase gene. 14723717 2004
Entrez Id: 406996
Gene Symbol: MIR214
MIR214 		0.010 Biomarker group BEFREE We investigated miR-124 and miR-214 expressions in serum and skin tissues of severe drug eruptions to evaluate the possibility of biomarkers of TEN. 26394757 2016
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B 		0.320 Biomarker group CTD_human [Correlation, in previously treated HIV-1 positive patients, between hypersensitivity reaction to abacavir and the presence of the HLA-B*5701 allele]. 19712599 2010
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1 		0.300 Biomarker group CTD_human [Relationship between gene polymorphism of CYP2E1, CYP1A1, IL-4 and medicamentosa-like dermatitis induced by trichloroethylene]. 19351467 2009
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1 		0.300 Biomarker group CTD_human [Relationship between gene polymorphism of CYP2E1, CYP1A1, IL-4 and medicamentosa-like dermatitis induced by trichloroethylene]. 19351467 2009