Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 Biomarker disease BEFREE HTx patients had lower lymphocyte, platelets, glucose, total proteins and albumin at T1; differences with LVAD patients vanished during rehabilitation when new cases of diabetes were observed in HTx. 30018333 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 Biomarker disease BEFREE In this study, we collected urine albumin/creatinine and urine protein/creatinine ratios on obese patients undergoing bariatric surgery to determine the prevalence of albuminuria and proteinuria in obese patients with and without associated diabetes and HTN. 29761105 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 GeneticVariation disease BEFREE Among whites, rs34459162, a novel missense single nucleotide polymorphism (SNP) in <i>RCN3</i>, was associated with fructosamine (<i>P</i> = 5.3 × 10<sup>-9</sup>) and rs1260236, a known diabetes-related missense mutation in <i>GCKR</i>, was associated with percent glycated albumin (<i>P</i> = 5.9 × 10<sup>-9</sup>) and replicated in CARDIA. 29844224 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 Biomarker disease BEFREE Multivariable Cox proportional hazards analyses adjusting for age, sex, body mass index, systolic blood pressure, fasting glucose, estimated glomerular filtration rate, uric acid, triglycerides, serum albumin, and the presence of diabetes and hypertension revealed that a decrease of 10% in the forced expiratory volume in 1s (FEV<sub>1</sub>)/forced vital capacity (FVC) ratio was associated with a 35% increase in the development of CKD during the follow-up. 29674361 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 AlteredExpression disease BEFREE Individuals with hematuria were more likely to be Hispanic (22% vs. 9.5%, respectively), have diabetes (56% vs. 48%), lower mean eGFR (40.2 vs. 45.3 ml/min/1.73 m2), and higher levels of urinary albumin > 1.0 g/day (36% vs. 10%). 29940877 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 Biomarker disease BEFREE In addition to the indicators of preoperative age, nutritional risk screening, body mass index, preoperative albumin, and diabetes, the NLR and PLR were independent predictors for sarcopenia (<i>P</i><0.05). 30464594 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 Biomarker disease BEFREE Finally, in glomeruli isolated from rats with early diabetes there was a significant increase in albumin permeability and loss of endothelial glycocalyx, both of which were ameliorated by angiopoietin-1. 29433915 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 GeneticVariation disease BEFREE 38 of 42 cohorts had multivariable survival analyses (MVSA) adjusting for age (92%), gender (66%), diabetes (63%), albumin (58%), inflammation (CRP/IL6-37%), non-BI nutritional markers (24%) and echocardiographic data (8%). 29535377 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 Biomarker disease BEFREE Urinary albumin excretion is an early sign of diabetic kidney disease, affecting every third individual with diabetes. 30120300 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 AlteredExpression disease BEFREE The beneficial impact of high albumin level on death was significantly greater for patients with older age (≥50 years), no diabetes, low ultrafiltration (UF) volume (<1000 mL/day), and low levels of serum creatinine (<10 mg/dL), total cholesterol (<177.5 mg/dL), ferritin (<100 ng/mL), and high-sensitivity C-reactive protein (hs-CRP) (<0.1 mg/dL). 29694445 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 AlteredExpression disease BEFREE We identified 58,182 patients diagnosed with diabetes from 2000-2008 and examined the level of performance for seven QoC measurements (HbA1c, LDL, albumin-creatinine-ratio, fundus/foot examinations, BMI and Blood-pressure) at diagnosis year. 30540832 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 Biomarker disease BEFREE The case mean was compared to charges for patients with modifiable risk factors: anemia (Hgb < 10 g/dL), malnutrition (albumin < 3.4 g/dL), obesity (body mass index > 45 kg/m<sup>2</sup>), uncontrolled diabetes (random glucose >180 mg/dL or A1C > 8), narcotic use (prescription filled), and tobacco use (documented within 30 days before surgery). 29807789 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 AlteredExpression disease BEFREE Significant differences among robust, pre-frail, and frail subjects were observed in terms of age, serum albumin level, alcohol consumption, smoking, and history of diabetes. 29484361 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 Biomarker disease BEFREE Conclusions Requesting of urinary albumin showed a significant regional variability in primary care in Spain, and was insufficient to correctly monitor patients with diabetes and arterial hypertension. 28656819 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 Biomarker disease BEFREE Diabetic kidney disease (DKD), defined as reduced glomerular filtration rate (GFR), elevated urine albumin excretion, or both that is clinically attributable to diabetes, is a common and morbid diabetes complication. 30282055 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 Biomarker disease BEFREE Clinical usefulness of Glycated Albumin in the diagnosis of diabetes: Results from an Italian study. 29486186 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 GeneticVariation disease BEFREE Higher baseline serum albumin concentration was not an independent risk factor of future T2D, whereas an increase in serum albumin concentration was independently associated with a lower diabetes risk. 29074121 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 Biomarker disease BEFREE Supporting these findings, diabetes metabolites (glycated albumin and high glucose) were able to modulate NLRP1 expression. 29031829 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 Biomarker disease BEFREE According to the guidelines of the Japanese Society for Dialysis Therapy (JSDT) regarding the treatment of diabetes in hemodialysis patients, the target casual plasma glucose level (predialysis blood glucose level) is less than 180-200 mg/dL, the target glycated albumin value is less than 20.0% (less than 24.0% in patients at risk of hypoglycemia). 30041202 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 Biomarker disease BEFREE Metabolomic screening identified 1,242 metabolites, out of which 111 differed significantly between progressors and non-progressors after adjustment for age of diabetes onset, baseline glycosylated hemoglobin A1c (HbA<sub>1c</sub>), and albumin excretion rate (AER). 30217994 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 Biomarker disease BEFREE The clinical usefulness of glycated albumin in patients with diabetes and chronic kidney disease: Progress and challenges. 30049445 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 GeneticVariation disease BEFREE This study aimed to investigate the effects of metformin and acarbose treatment on urine albumin excretion in Chinese patients with newly diagnosed diabetes and low-grade albuminuria. 30531690 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 AlteredExpression disease BEFREE Therefore, we propose albumin level and its glycation status to be quantified in conjunction with HbA1c for better management of diabetes. 30411025 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 Biomarker disease BEFREE Because diabetes is a progressive disease, the effect of glycated albumin on liraglutide affinity found here is important to consider when diabetes is managed with this drug. 29414771 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 Biomarker disease BEFREE The role of albumin reabsorption in proximal tubule (PT) cells has emerged as an important factor in the genesis of albuminuria observed in the early stages of diabetes. 29871929 2018