Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | GeneticVariation | disease | BEFREE | Several investigations have been conducted regarding the interaction between Apolipoprotein A2 (APOA2) -265 T>C polymorphism and dietary intake of saturated fatty acids (SFAs) on obesity in healthy individuals or type 2 diabetes mellitus (T2 DM) patients. | 28359369 | 2017 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Since the interaction between APOA2 polymorphism and dietary fatty acids on oxidative stress has not yet discussed, we aimed to investigate the interaction on oxidative stress in type 2 diabetes mellitus (T2DM) patients. | 27271094 | 2017 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | APOA II genotypes frequency and their interaction with saturated fatty acids consumption on lipid profile of patients with type 2 diabetes. | 26210798 | 2016 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Association between ApoA-II -265T/C polymorphism and oxidative stress in patients with type 2 diabetes mellitus. | 26104730 | 2016 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | The available data does not support a role for common variants in APOA2 on type 2 diabetes susceptibility or related quantitative traits in Northern Europeans. | 19216768 | 2009 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | This, and the location of the apoA-II gene in chromosome 1q23, a hot region in the search for genes associated with familial combined hyperlipidemia, insulin resistance and type 2 diabetes mellitus, has greatly increased interest in this protein. | 15166779 | 2004 | ||||
|
0.080 | Biomarker | disease | BEFREE | Apolipoprotein A-II is not likely to explain the observed linkage of Type II diabetes, but variation in this gene could alter insulin secretion and post-challenge glucose. | 12136402 | 2002 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Studies of human beings have shown the apoA-II locus to be a determinant of FFA plasma levels, and several genome-wide searches of different populations with type 2 diabetes have found linkage to an apoA-II intragenic marker, making apoA-II an attractive candidate gene for this disease. | 11714842 | 2001 |