Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
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0.570 | Biomarker | disease | BEFREE | FGF23 and Klotho Levels are Independently Associated with Diabetic Foot Syndrome in Type 2 Diabetes Mellitus. | 30987161 | 2019 | ||||
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0.570 | AlteredExpression | disease | BEFREE | Our results suggest that circulating Klotho level is a predictor of long-term macrovascular outcomes in patients with type 2 diabetes. | 30048945 | 2018 | ||||
|
0.570 | AlteredExpression | disease | BEFREE | The effect of pentoxifylline on Klotho levels in patients with type 2 diabetes mellitus with chronic kidney disease (CKD) was assessed in a post hoc analysis of the Pentoxifylline for Renoprotection in Diabetic Nephropathy (PREDIAN) trial. | 29866645 | 2018 | ||||
|
0.570 | AlteredExpression | disease | BEFREE | Our findings indicate that serum Klotho levels were associated with the development of T2DM, and long-term control of blood glucose will be beneficial in ameliorating changes to α-Klotho and β-Klotho levels in patients with T2DM and complications. | 30042059 | 2018 | ||||
|
0.570 | Biomarker | disease | CTD_human | Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease. | 28869590 | 2017 | ||||
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0.570 | AlteredExpression | disease | BEFREE | Serum levels of α-Klotho and β-Klotho are down-regulated in patients with T2DM. | 27916483 | 2017 | ||||
|
0.570 | AlteredExpression | disease | BEFREE | We investigated if sKlotho levels are decreased in type 2 diabetes and associate with MVD in the absence of diabetic nephropathy, and whether hyperglycemia affects renal Klotho production in vitro and in vivo. | 23945089 | 2013 | ||||
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0.570 | Biomarker | disease | RGD | Renal expression of FGF23 in progressive renal disease of diabetes and the effect of ACE inhibitor. | 23967103 | 2013 | ||||
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0.570 | Biomarker | disease | BEFREE | We performed a large case-control and family-based study to test the hypothesis that KL-VS is associated with type 2 diabetes in a UK Caucasian population. | 16753056 | 2006 |