Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8085
Gene Symbol: KMT2D
KMT2D
0.050 GeneticVariation disease BEFREE To provide a more precise evaluation of the association between the (CA)n variations of ALR and the risk for DR, a meta-analysis was performed in the present study. 31777552 2019
Entrez Id: 8085
Gene Symbol: KMT2D
KMT2D
0.050 Biomarker disease BEFREE Inhibition of ALR may also be an ideal target for reducing the deleterious effects of DR. 27835059 2017
Entrez Id: 8085
Gene Symbol: KMT2D
KMT2D
0.050 GeneticVariation disease BEFREE Our meta-analysis showed that ALR C-106T variants appear to influence the risk for DR in Chinese Han persons. 26580232 2016
Entrez Id: 8085
Gene Symbol: KMT2D
KMT2D
0.050 GeneticVariation disease BEFREE Overall, the pooled ORs showed a nonsignificant association between ALR C(-106)T polymorphism and DR susceptibility in all genetic models (C allele versus T allele: OR = 1.08, 95% CI = 0.90-1.29; CT/TT versus CC: OR = 0.90, 95% CI = 0.72-1.13; TT versus 25722213 2015
Entrez Id: 8085
Gene Symbol: KMT2D
KMT2D
0.050 GeneticVariation disease BEFREE A recent meta-analysis found genetic variation in the ALR gene (AKR1B1) to be significantly associated with diabetic retinopathy (DR). 20424224 2010