Gene: MAP2K7 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5609
Gene Symbol: MAP2K7
MAP2K7 		0.040 GeneticVariation group BEFREE Patients with ECD appear to require substantially reduced doses of BRAF and MEK inhibitors but are responsive to these lower doses. 31740567 2019
Entrez Id: 5609
Gene Symbol: MAP2K7
MAP2K7 		0.040 Biomarker group BEFREE We review the radiologic hallmarks of ECD and demonstrate the radiologic manifestations of response to combined BRAF and MEK inhibitor treatment. 29485431 2018
Entrez Id: 5609
Gene Symbol: MAP2K7
MAP2K7 		0.040 Biomarker group BEFREE This case contributes to the ongoing efforts of simultaneous BRAF/MEK inhibition as a promising strategy in ECD. 27940476 2017
Entrez Id: 5609
Gene Symbol: MAP2K7
MAP2K7 		0.040 Biomarker group BEFREE Our results underscore the central role of RAS-RAF-MEK-ERK activation in ECD and identify an important role of activation of RAS-PI3K-AKT signaling in ECD. 25150293 2014