Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4513
Gene Symbol: COX2
COX2
0.040 Biomarker disease BEFREE Rats with esophagitis received intragastric (i.g.) pretreatment either with: 1) vehicle (saline), 2) ASA or NO-ASA (100 mg/kg); 3) the non-selective COX inhibitor, indomethacin (5 mg/kg); 4) the selective COX-1 inhibitor, SC-560 (10 mg/kg), and 5) the selective COX-2 inhibitor, celecoxib (5 mg/kg). 21451212 2011
Entrez Id: 4513
Gene Symbol: COX2
COX2
0.040 AlteredExpression disease BEFREE Cox-2 gene expression is increased in the distal esophageal squamous mucosa of most patients with GERD, and the elevation was similar whether there was mucosal injury in the form of esophagitis or Barrett's or no visible mucosal injury. 16863546 2006
Entrez Id: 4513
Gene Symbol: COX2
COX2
0.040 AlteredExpression disease BEFREE COX-2 protein levels were found to be increased in distal BE > proximal BE > oesophagitis > NE (P < 0.001). 15878911 2005
Entrez Id: 4513
Gene Symbol: COX2
COX2
0.040 AlteredExpression disease BEFREE There was also no significant increase in COX-2 expression in patients with esophagitis or in those who used nonsteroidal anti-inflammatory drugs. 15249402 2004