Gene: FANCI ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 55215
Gene Symbol: FANCI
FANCI 		0.500 Biomarker disease GENOMICS_ENGLAND To this end, the Fanconi Anemia pathway employs a unique nuclear protein complex that ubiquitinates FANCD2 and FANCI, leading to formation of DNA repair structures. 19686080 2009
Entrez Id: 55215
Gene Symbol: FANCI
FANCI 		0.500 Biomarker disease BEFREE This fact and novel data sustaining greater functional relevance of the three genes within the FA pathway prompted us to scrutinize all coding sequences and splicing sites of FANCI, FANCL and FANCM in 95 BRCA1/2-negative index cases from Spanish high-risk breast cancer families. 19737859 2009
Entrez Id: 55215
Gene Symbol: FANCI
FANCI 		0.500 AlteredExpression disease LHGDN We propose that the multiple phosphorylation of FANCI serves as a molecular switch in activation of the Fanconi anemia pathway. 18931676 2008
Entrez Id: 55215
Gene Symbol: FANCI
FANCI 		0.500 Biomarker disease BEFREE Here, we show that the FA core complex is required for efficient spontaneous and UVC-induced point mutagenesis, independently of FANCD2 and FANCI. 18448394 2008
Entrez Id: 55215
Gene Symbol: FANCI
FANCI 		0.500 Biomarker disease BEFREE The Fanconi anemia (FA) core complex promotes the tolerance/repair of DNA damage at stalled replication forks by catalyzing the monoubiquitination of FANCD2 and FANCI. 18851838 2008
Entrez Id: 55215
Gene Symbol: FANCI
FANCI 		0.500 AlteredExpression disease BEFREE We propose that the multiple phosphorylation of FANCI serves as a molecular switch in activation of the Fanconi anemia pathway. 18931676 2008
Entrez Id: 55215
Gene Symbol: FANCI
FANCI 		0.500 Biomarker disease LHGDN Mutation in FANCI is responsible for loss of a functional FA pathway in a patient with Fanconi anemia complementation group I. 17412408 2007
Entrez Id: 55215
Gene Symbol: FANCI
FANCI 		0.500 Biomarker disease GENOMICS_ENGLAND Knock-down of KIAA1794 expression by siRNA in HeLa cells caused excessive chromosomal breakage induced by mitomycin C, a hallmark of FA cells. 17452773 2007
Entrez Id: 55215
Gene Symbol: FANCI
FANCI 		0.500 Biomarker disease BEFREE Mutation in FANCI is responsible for loss of a functional FA pathway in a patient with Fanconi anemia complementation group I. 17412408 2007
Entrez Id: 55215
Gene Symbol: FANCI
FANCI 		0.500 Biomarker disease LHGDN A FANCD2 protein sequence-based homology search facilitated the discovery of FANCI, a second monoubiquitinated component of the FA pathway. 17460694 2007
Entrez Id: 55215
Gene Symbol: FANCI
FANCI 		0.500 Biomarker disease LHGDN Knock-down of KIAA1794 expression by siRNA in HeLa cells caused excessive chromosomal breakage induced by mitomycin C, a hallmark of FA cells. 17452773 2007
Entrez Id: 55215
Gene Symbol: FANCI
FANCI 		0.500 Biomarker disease BEFREE A FANCD2 protein sequence-based homology search facilitated the discovery of FANCI, a second monoubiquitinated component of the FA pathway. 17460694 2007
Entrez Id: 55215
Gene Symbol: FANCI
FANCI 		0.500 Biomarker disease GENOMICS_ENGLAND Positional cloning of a novel Fanconi anemia gene, FANCD2. 11239453 2001
Entrez Id: 55215
Gene Symbol: FANCI
FANCI 		0.500 GeneticVariation disease CLINVAR