<i>In vivo</i> assays also indicated that lncRNA HOXA11-AS inhibitor could inhibit glioma growth <i>in vivo</i> by regulating the expression of miR-125a.
Long non-coding RNA HOXA11 antisense RNA (HOXA11-AS) has been previously reported to be involved in the tumorigenesis and progression of ovarian cancer and glioma.
Multivariate Cox regression analysis revealed that HOXA11-AS was an independent prognostic factor in glioblastoma multiforme patients, and its expression was correlated with the glioma molecular subtypes of the Cancer Genome Atlas.