| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | Biomarker | disease | BEFREE | NEAT1 regulated CDK6 to affect glioma growth through sponging miR-139-5p. | 30515782 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | Our results indicate that miR-139-3p plays a significant role in controlling behaviors associated with the malignant progression of gliomas, and we identify the miR-139-3p-syntenin axis as a potential therapeutic target for glioma. | 30502089 | 2019 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | In the present study, we demonstrate that miR‑139‑5p inhibits Flt1 expression mediated by binding its 3' untranslated region (3'UTR) to regulate the progression of human glioma. | 29393392 | 2018 | ||||
|
0.080 | Biomarker | disease | BEFREE | MiR-139-5p overexpression partially phenocopied Notch1 siRNA, whereas the forced expression of Notch1 reversed the effects of miR-139-5p on the invasion of glioma. | 30170559 | 2018 | ||||
|
0.080 | Biomarker | disease | BEFREE | In this study, we not only validated the low expression level of miR-139 in glioma tissues and cell lines but also detected the effect of miR-139 on modulating gliomas proliferation and invasion both in vitro and in vivo. | 26868851 | 2017 | ||||
|
0.080 | Biomarker | disease | BEFREE | In conclusion, this study demonstrated that the HCP5-microRNA-139- Runt-related transcription factor 1 feedback loop plays a pivotal role in regulating the malignant behavior of glioma cells, which may provide a potential therapeutic strategy for treating glioma. | 27434586 | 2016 | ||||
|
0.080 | Biomarker | disease | BEFREE | Bioinformatics coupled with luciferase and western blot assays also revealed that miR-139-5p suppresses glioma cell proliferation by targeting ELTD1 and regulating cell cycle. | 26449464 | 2015 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | MiR-139 inhibits Mcl-1 expression and potentiates TMZ-induced apoptosis in glioma. | 23551751 | 2013 |