| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | Biomarker | disease | BEFREE | Circulating CD89-IgA complex does not predict deterioration of kidney function in Korean patients with IgA nephropathy. | 28672768 | 2017 | ||||
|
0.090 | Biomarker | disease | BEFREE | In patients, however, CD89/IgA complexes were detected, and injection of patient IgA induced IgAN-like features in CD89 Tg mice. | 27437939 | 2016 | ||||
|
0.090 | Biomarker | disease | BEFREE | This result does, however, not preclude the implication of other CD89 polymorphisms neither the possibility for a role of CD89 in the pathogenesis of IgA nephropathy. | 21750160 | 2012 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Our results provide evidence for genetic variation at the putative promoter region of FCAR conferring susceptibility to IgAN, suggesting -27C and its haplotype may be causative for the susceptibility among the Chinese Han population. | 21273231 | 2011 | ||||
|
0.090 | Biomarker | disease | BEFREE | Understanding how IgA triggers shedding of CD89 from myeloid cell surfaces could help clarify the process of immune complex formation in IgAN, and measurement of this soluble form of CD89 may in the future prove a useful prognostic indicator of end-stage renal disease in this common glomerulonephritis. | 21116273 | 2010 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | However, no association between CD89 gene polymorphisms and susceptibility to IgAN was detected. | 20811333 | 2010 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Genetic polymorphisms in the promoter and 5' UTR region of the Fc alpha receptor (CD89) are not associated with a risk of IgA nephropathy. | 11776381 | 2001 | ||||
|
0.090 | Biomarker | disease | BEFREE | Fcalpha receptor (CD89) mediates the development of immunoglobulin A (IgA) nephropathy (Berger's disease). Evidence for pathogenic soluble receptor-Iga complexes in patients and CD89 transgenic mice. | 10839814 | 2000 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | IgA nephropathy-specific expression of the IgA Fc receptors (CD89) on blood phagocytic cells. | 9367406 | 1997 |