Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3040
Gene Symbol: HBA2
HBA2
0.360 GeneticVariation disease BEFREE Analysis of deletional hereditary persistence of fetal hemoglobin/δβ-thalassemia and δ-globin gene mutations in Southerwestern China. 31044540 2019
Entrez Id: 3040
Gene Symbol: HBA2
HBA2
0.360 Biomarker disease CTD_human Interaction of hemoglobin and copper nanoparticles: implications in hemoglobinopathy. 17292142 2006
Entrez Id: 3040
Gene Symbol: HBA2
HBA2
0.360 GeneticVariation disease BEFREE The pattern of inheritance of several polymorphic restriction sites associated with the beta-gene cluster, and spanning a region of 52kb, demonstrates that a determinant for hereditary persistence of fetal hemoglobin (HPFH) segregates independently from the non-alpha globin gene cluster, as we postulated several years ago on purely genetical grounds. 2472351 1989
Entrez Id: 3040
Gene Symbol: HBA2
HBA2
0.360 GeneticVariation disease BEFREE Persistent expression of the gamma-globin gene in adult life has been supposed to be caused by loss of a region located about 3-4 kb 5' to the delta-globin gene from comparison of the extents of deletions in several different forms of delta beta-thalassemia and HPFH (hereditary persistence of fetal hemoglobin). 2982369 1985
Entrez Id: 3040
Gene Symbol: HBA2
HBA2
0.360 GeneticVariation disease BEFREE The possible linkage between a gene causing heterocellular hereditary persistence of fetal hemoglobin (HPFH) and human non-alpha globin loci has been studied in a large Sardinian family. 6196196 1983
Entrez Id: 3040
Gene Symbol: HBA2
HBA2
0.360 AlteredExpression disease BEFREE Comparison of these deletions with previously described ones in Negro and in a new Southern Italian case of hereditary persistence of fetal hemoglobin suggests that the deletion of a region centered at a cluster of repetitive sequences approximately 3.5 kilobases 5' to the delta-globin gene may be critical for the persistent expression of high levels of gamma-globin in hereditary persistence of fetal hemoglobin compared to delta beta-thalassemia. 6179097 1982
Entrez Id: 3040
Gene Symbol: HBA2
HBA2
0.360 GeneticVariation disease BEFREE We observed the total deletion of alpha-globin genes in homozygous alpha-thalassemia (hydrops fetalis with hemoglobin Bart's) and the deletion of particular beta and beta-like sequences in cases homozygous for hereditary persistence of fetal hemoglobin and deltabeta-thalassemia. 661890 1978