Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2006
Gene Symbol: ELN
ELN 		0.510 Biomarker phenotype CTD_human Increased tropoelastin and procollagen expression in the lung of nitrofen-induced diaphragmatic hernia in rats. 10359170 1999
Entrez Id: 7490
Gene Symbol: WT1
WT1 		0.510 Biomarker phenotype MGD The Wilms tumor suppressor gene wt1 is required for development of the spleen. 10469569 1999
Entrez Id: 23414
Gene Symbol: ZFPM2
ZFPM2 		0.510 GeneticVariation phenotype BEFREE Candidate genes for congenital diaphragmatic hernia from animal models: sequencing of FOG2 and PDGFRalpha reveals rare variants in diaphragmatic hernia patients. 17568391 2007
Entrez Id: 7490
Gene Symbol: WT1
WT1 		0.510 AlteredExpression phenotype BEFREE The expression of the WT1 gene in pleural and abdominal mesothelium and the occurrence of diaphragmatic hernia in transgenic mice with a homozygous WT1 deletion strongly suggests that the diaphragmatic hernia in this patient is part of the malformation pattern caused by WT1 mutations. 7645607 1995
Entrez Id: 2627
Gene Symbol: GATA6
GATA6 		0.510 Biomarker phenotype RGD Downregulation of GATA4 and GATA6 in the heart of rats with nitrofen-induced diaphragmatic hernia. 18280291 2008
Entrez Id: 2006
Gene Symbol: ELN
ELN 		0.510 Biomarker phenotype RGD Effect of mechanical ventilation on the pulmonary expression and production of elastin in nitrofen-induced diaphragmatic hernia in rats. 12194112 2002
Entrez Id: 23414
Gene Symbol: ZFPM2
ZFPM2 		0.510 Biomarker phenotype MGD FOG2 is the first gene implicated in the pathogenesis of nonsyndromic human congenital diaphragmatic defects, and its necessity for pulmonary development validates the hypothesis that neonates with congenital diaphragmatic hernia may also have primary pulmonary developmental abnormalities. 16103912 2005
Entrez Id: 23414
Gene Symbol: ZFPM2
ZFPM2 		0.510 GeneticVariation phenotype LHGDN Candidate genes for congenital diaphragmatic hernia from animal models: sequencing of FOG2 and PDGFRalpha reveals rare variants in diaphragmatic hernia patients. 17568391 2007
Entrez Id: 2627
Gene Symbol: GATA6
GATA6 		0.510 Biomarker phenotype CTD_human Downregulation of GATA4 and GATA6 in the heart of rats with nitrofen-induced diaphragmatic hernia. 18280291 2008
Entrez Id: 2006
Gene Symbol: ELN
ELN 		0.510 AlteredExpression phenotype BEFREE Effect of mechanical ventilation on the pulmonary expression and production of elastin in nitrofen-induced diaphragmatic hernia in rats. 12194112 2002
Entrez Id: 2627
Gene Symbol: GATA6
GATA6 		0.510 GeneticVariation phenotype BEFREE A novel GATA6 variant in a boy with neonatal diabetes and diaphragmatic hernia: a familial case with a review of the literature. 31271559 2019
Entrez Id: 7490
Gene Symbol: WT1
WT1 		0.510 Biomarker phenotype CTD_human Genetic factors in congenital diaphragmatic hernia. 17436238 2007
Entrez Id: 23414
Gene Symbol: ZFPM2
ZFPM2 		0.510 Biomarker phenotype CTD_human Genetic factors in congenital diaphragmatic hernia. 17436238 2007
Entrez Id: 7490
Gene Symbol: WT1
WT1 		0.510 Biomarker phenotype MGD Teratogen-induced, dietary and genetic models of congenital diaphragmatic hernia share a common mechanism of pathogenesis. 17071579 2006
Entrez Id: 7026
Gene Symbol: NR2F2
NR2F2 		0.500 Biomarker phenotype MGD
Entrez Id: 7080
Gene Symbol: NKX2-1
NKX2-1 		0.500 Biomarker phenotype CTD_human Effects of antioxidant vitamins on molecular regulators involved in lung hypoplasia induced by nitrofen. 16863852 2006
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.500 Biomarker phenotype CTD_human Antenatal dexamethasone suppresses tumor necrosis factor-alpha expression in hypoplastic lung in nitrofen-induced diaphragmatic hernia in rats. 10541330 1999
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		0.500 Biomarker phenotype CTD_human Administration of antenatal glucocorticoids upregulates peptide growth factor gene expression in nitrofen-induced congenital diaphragmatic hernia in rats. 10646786 2000
Entrez Id: 3481
Gene Symbol: IGF2
IGF2 		0.500 Biomarker phenotype CTD_human Effect of antenatal glucocorticoid administration on insulin-like growth factor I and II levels in hypoplastic lung in nitrofen-induced congenital diaphragmatic hernia in rats. 10370016 1999
Entrez Id: 7080
Gene Symbol: NKX2-1
NKX2-1 		0.500 Biomarker phenotype RGD Impaired alveolar epithelial cell differentiation in the hypoplastic lung in nitrofen-induced congenital diaphragmatic hernia. 17245593 2007
Entrez Id: 7080
Gene Symbol: NKX2-1
NKX2-1 		0.500 Biomarker phenotype CTD_human Down-regulation of thyroid transcription factor-1 gene expression in fetal lung hypoplasia is restored by glucocorticoids. 10830305 2000
Entrez Id: 2626
Gene Symbol: GATA4
GATA4 		0.500 Biomarker phenotype CTD_human Downregulation of GATA4 and GATA6 in the heart of rats with nitrofen-induced diaphragmatic hernia. 18280291 2008
Entrez Id: 652
Gene Symbol: BMP4
BMP4 		0.500 Biomarker phenotype RGD Downregulation of GATA4 and GATA6 in the heart of rats with nitrofen-induced diaphragmatic hernia. 18280291 2008
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		0.500 Biomarker phenotype CTD_human Pulmonary endothelial nitric oxide synthase gene expression is decreased in a rat model of congenital diaphragmatic hernia. 7576705 1995
Entrez Id: 6586
Gene Symbol: SLIT3
SLIT3 		0.500 Biomarker phenotype MGD Heparan sulfate deficiency disrupts developmental angiogenesis and causes congenital diaphragmatic hernia. 24355925 2014