Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.100 Biomarker disease BEFREE Although neonates and infants with group B streptococcal or <i>E coli</i> meningitis had similar age and CSF laboratory values, patients with group B streptococcal meningitis more frequently demonstrated infarcts, while those with <i>E coli</i> meningitis more frequently had early onset of hydrocephalus. 31320464 2019
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.100 AlteredExpression disease BEFREE Based on the changes in CSF levels of SP-G in hydrocephalus, brain hemorrhage, and CNS infections as well as its abundance at CSF flow-related anatomical structures closely associated with immunological barrier systems, importance for CSF rheology, brain waste clearance, and host defense is assumable. 30032421 2019
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.100 GeneticVariation disease BEFREE Complications included hydrocephalus (12), CSF leak/pseudomeningocele (11), wound infection (9), postoperative hematoma (4), venous infarction (1), and pneumocephalus (1). 29726777 2018
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.100 Biomarker disease BEFREE Duraplasty (n = 101) was complicated by CSF leak in 4.0% (n = 4), symptomatic pseudomeningocele in 4.0% (n = 4), aseptic meningitis in 2.0% (n = 2) and hydrocephalus in 1.0% (n = 1). 30737652 2019
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.100 GeneticVariation disease BEFREE Endoscopic third ventriculostomy is a well-accepted treatment choice for hydrocephalus and is used most frequently with a known impediment to CSF flow between the third ventricle and basal cisterns. 30442699 2018
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.100 Biomarker disease BEFREE For patients with ePFTs, petroclival/midline tumor location (OR 12.2/OR 5.7), perilesional edema (OR 10.0), and preoperative hydrocephalus (OR 4.0) were independent predictors of need for CSF drainage. 30611134 2019
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.100 GeneticVariation disease BEFREE Here, the authors describe their institutional experience managing patients with extreme neonatal hydrocephalus with CSF diversion, with and without CVRF, over the past 12 years. 29498604 2018
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.100 Biomarker disease BEFREE Here, we report a case where a patient with subarachnoid haemorrhage (SAH) with acute hydrocephalus needed CSF diversion and had an EVD, during replacement of which through the same tract, the new EVD went into the sellar floor and she developed diabetes insipidus (DI) eventually. 31073783 2019
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.100 Biomarker disease BEFREE Higher FA in specific periventricular white matter tracts, tending toward FA in controls, was associated with increased ventricular size, as well as improved clinical outcome.CONCLUSIONSThe study shows that TBSS-based DTI is a sensitive technique for elucidating changes in white matter structures due to hydrocephalus and chronic CSF shunting and provides preliminary evidence that DTI may be a valuable tool for tailoring shunt procedures to monitor ventricular size following shunting and achieve optimal outcome, as well as for guiding the development of alternate therapies for hydrocephalus. 29350598 2018
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.100 GeneticVariation disease BEFREE In non-syndromic CIM subjects, the presence of hydrocephalus could be explained by an occlusion of the basal CSF pathways, which would occur completely in a minority of cases (only 7-10% of CIM patients show hydrocephalus) while it would be partial in the remaining cases (no hydrocephalus). 31227858 2019
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.100 GeneticVariation disease BEFREE In this retrospective study, the phase-contrast MR imaging of 185 patients with suspected chronic adult hydrocephalus was evaluated using the CSF Flow software package. 30467214 2018
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.100 Biomarker disease BEFREE Intraventricular endoscopic cyst drainage allows resolution of hydrocephalus with restoration of normal intracranial pressure, gives time for proper preoperative work up, and has reduced incidence of CSF leak after transnasal surgery. 29435609 2018
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.100 Biomarker disease BEFREE Management of hydrocephalus followed a stepwise algorithm to determine the need for external CSF drainage and subsequent shunt placement. 29957109 2018
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.100 Biomarker disease BEFREE OBJECTIVE Endoscopic third ventriculostomy (ETV) is a surgical alternative to placing a CSF shunt in certain patients with hydrocephalus. 28686122 2017
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.100 Biomarker disease BEFREE OBJECTIVE Up to one-third of patients with a posterior fossa brain tumor (PFBT) will experience persistent hydrocephalus mandating permanent CSF diversion. 28291428 2017
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.100 Biomarker disease BEFREE Of these, 10.5% (39/373) required permanent CSF shunting due to persisting postoperative HC. 30120611 2020
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.100 Biomarker disease BEFREE On the other side, a positive mismatch, consisting of intracranial content higher than skull volume, usually depends on CSF collection or hydrocephalus once the brain edema is regressed. 31134339 2019
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.100 GeneticVariation disease BEFREE Other surgical complications included haematoma (0.3%), hydrocephalus (0.3%) and CSF leak (1.2%).None had permanent complications. 28324680 2017
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.100 GeneticVariation disease BEFREE Our follow-up results are comparable with those of previous, larger studies and confirm the efficacy of treating hydrocephalus with ETV in selected cases and with CSF shunt only in cases of clearly increased intracranial pressure. 30259717 2018
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.100 GeneticVariation disease BEFREE Outcomes included symptomatic hydrocephalus requiring CSF drainage, need for ventriculoperitoneal shunt, radiographic vasospasm, delayed cerebral ischemia (DCI), radiographic infarction, disability level within 1 year of ictus, and at last clinical follow-up as defined by the modified Rankin Scale. 30996058 2019
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.100 GeneticVariation disease BEFREE Patients were followed prospectively for time to treatment failure, defined as the need for repeat CSF diversion procedure (shunt or ETV) or death due to hydrocephalus. 28357554 2017
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.100 GeneticVariation disease BEFREE PDC versus graft dural closure (GDC; 35% vs 7%, OR 5.88, 95% CI 2.94-50.0, p = 0.03) and hydrocephalus ultimately requiring permanent CSF diversion (OR 3.30, 95% CI 1.07-10.19, p = 0.0007) were associated with wound infection requiring surgical debridement. 31783365 2019
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.100 Biomarker disease BEFREE Real-time MRI access to CSF flow in response to defined respiration patterns will be of clinical importance for patients with disturbed CSF circulation like hydrocephalus, pseudotumor cerebri and others. 30947716 2019
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.100 Biomarker disease BEFREE Reliability of CSF turbulence and choroid plexus visualization on fast-sequence MRI in pediatric hydrocephalus. 29076795 2018
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.100 GeneticVariation disease BEFREE Results showed that the intensity of clinical symptoms was similar in patients with similar CSF pressure and the cause of the hydrocephalus disease didn't have any significant effect on the intensity of patients' clinical symptoms and the manner of changes in effective parameters on disease. 27773546 2017