Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 213
Gene Symbol: ALB
ALB
0.400 Biomarker group BEFREE The masked hypertension group had a greater risk for stroke compared with the controlled BP group (hazard ratio, 2.77; 95% CI, 1.20-6.37), independent of traditional cardiovascular risk factors, urine albumin to creatinine ratio, and circulating B-type natriuretic peptide levels. 29800067 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.400 Biomarker group BEFREE Factors significantly associated with C-AKI included age 61 to 70 years (odds ratio [OR], 1.64 [95% CI, 1.21 to 2.23]; P = .001) and 71 to 90 years (OR, 2.97 [95% CI, 2.06 to 4.28]; P < .001) compared with ≤ 60 years; cisplatin dose 101 to 150 mg (OR, 1.58 [95% CI, 1.14 to 2.19]; P = .007) and > 150 mg (OR, 3.73 [95% CI, 2.68 to 5.20]; P < .001) compared with ≤ 100 mg; a history of hypertension (OR, 2.10 [95% CI, 1.54 to 2.72]; P < .001) compared with no hypertension; and serum albumin 2.0 to 3.5 g/dL (OR, 2.21 [95% CI, 1.62 to 3.03]; P < .001) compared with > 3.5 g/dL. 29320311 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.400 Biomarker group BEFREE In this study, we collected urine albumin/creatinine and urine protein/creatinine ratios on obese patients undergoing bariatric surgery to determine the prevalence of albuminuria and proteinuria in obese patients with and without associated diabetes and HTN. 29761105 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.400 Biomarker group BEFREE A multivariate analysis found albumin < 3.5 g/dL (OR 2.04: 95% CI 1.0-4.2, p < 0.05) and hypertension (OR 4.6: 95% CI 2.3-9.2, p < 0.001) as variables independently associated with AE occurrence.The SVR12 was 95% (228/240). 29808463 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.400 Biomarker group BEFREE To our findings, higher dietary antioxidant capacity was associated with lower prevalence of hypertension, lower hematocrit, total cholesterol and higher albumin and vitamin D concentrations. 30540842 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.400 Biomarker group BEFREE After being fed the high-salt diet, SS rats fed high protein had amplified hypertension and albumin excretion (158.7 ± 2.6 mmHg and 140.8 ± 16.0 mg/day, respectively, means ± SE) compared with SS rats fed normal protein (139.4 ± 3.6 mmHg and 69.4 ± 11.3 mg/day). 29537860 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.400 Biomarker group BEFREE Control of hypertension (predialysis blood pressure, number of antihypertensives), phosphate (phosphate, number of phosphate binders), nutritional status and inflammation (albumin, C reactive protein and postdialysis weight) and anaemia (erythropoiesis-stimulating agent (ESA) resistance). 29523566 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.400 Biomarker group BEFREE Elevated urinary albumin excretion is more likely to precede hypertension. 30571489 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.400 Biomarker group BEFREE Twelve features were selected to compose the optimal feature sets, including body temperature (T), glucose (GLU), creatine kinase (CK), albumin (ALB), hydroxybutyrate dehydrogenase (HBDH), blood urea nitrogen (BUN), uric Acid (UA), creatinine (Crea), cholesterol (TC), total protein (TP), pulse (P), and respiration (R).SVM can be used to distinguish patients having both hypertension and depression from those having hypertension alone. 30095631 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.400 Biomarker group BEFREE Moreover, the effect of low serum albumin on the risk of MCI was further enhanced among the subjects with hypertension, diabetes, hyperlipemia, cardiovascular disease, cerebrovascular disease, high serum levels of C-reactive protein, or relatively low levels of uric acid or total bilirubin. 30249938 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.400 Biomarker group BEFREE Conclusions Requesting of urinary albumin showed a significant regional variability in primary care in Spain, and was insufficient to correctly monitor patients with diabetes and arterial hypertension. 28656819 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.400 Biomarker group BEFREE Compared with the lowest level of serum NT-proBNP tertile (≤36 pg/mL), the highest level of serum NTproBNP tertile (≥84 pg/mL) showed increased risk of incident CKD after adjusting age, sex, body mass index, hemoglobin A1c, creatinine, smoking, usage of hypertension drug and urinary albumin excretion at baseline examination (adjusted HR2.37, 95% CI 1.09-5.48, p = 0.028). 29697035 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.400 AlteredExpression group BEFREE Multivariate analysis showed that male sex, a history of smoking, high systolic blood pressure, high body mass index, high levels of fasting glucose and total cholesterol, low levels of albumin and hemoglobin, and a low estimated glomerular filtration rate were associated with abnormal echocardiographic findings. 29581872 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.400 AlteredExpression group BEFREE Patients who developed chronic kidney disease were older at onset of lupus nephritis, had less education, and were more likely to have hypertension; they had lower serum albumin levels, lower platelet levels, higher serum creatinine levels, lower estimated glomerular filtration rate, higher chronicity index, and lower frequency of anti-ribosomal P antibodies, and they were less likely to be in complete remission in the first year. 28420060 2017
Entrez Id: 213
Gene Symbol: ALB
ALB
0.400 Biomarker group BEFREE Independent factors (P < 0.05) associated with mortality in the multivariable Cox model in early dialysis start were: hypertension (HR 9.32, CI: 1.34-17.87), diabetes (HR 1.8, CI: 0.4-13.2) and albumin <3.5 g/dL (HR 1.5, CI: 0.8-6.2). 29205888 2017
Entrez Id: 213
Gene Symbol: ALB
ALB
0.400 Biomarker group BEFREE Multivariate logistic regression analysis showed that H-type hypertension is associated with serum albumin, uric acid, estimated glomerular filtration rate (eGFR), and 24-hour systolic blood pressure. 27440006 2017
Entrez Id: 213
Gene Symbol: ALB
ALB
0.400 Biomarker group BEFREE The diabetic-hypertensive right kidneys in GK-AC rats had much greater increases in albumin excretion and histological injury compared with left kidneys (diabetes mellitus only) of GK rats or right kidneys (hypertension only) of Wistar-AC rats. 28348018 2017
Entrez Id: 213
Gene Symbol: ALB
ALB
0.400 Biomarker group BEFREE PDE5i treatment prevented the development of DN-related hypertension (P < 0.001), the increase of urine albumin creatinine ratio (P < 0.01), the fall in glomerular filtration rate (P < 0.001), and improved renal resistive index (P < 0.001) and kidney microcirculation. 28294194 2017
Entrez Id: 213
Gene Symbol: ALB
ALB
0.400 GeneticVariation group BEFREE If patients did not have hypoproteinaemia or had hypertension, the SNP in rs1045642 was associated with CR (CC vs. TT: albumin ≥35, P = 0.042; hypertension, P = 0.045; C vs. T: albumin ≥35, P = 0.033; hypertension, P = 0.040). 28358842 2017
Entrez Id: 213
Gene Symbol: ALB
ALB
0.400 Biomarker group BEFREE To study elderly hypertensive patients with trace albuminuria (urine albumin to creatinine ratio (UACR)) and the relationship between the occurrence of new cardiovascular events, to provide a basis for early prevention in elderly patients with high blood pressure. 28770952 2017
Entrez Id: 213
Gene Symbol: ALB
ALB
0.400 Biomarker group BEFREE Collectively, these results indicate that both the glomerulus and the PT contribute to albuminuria, and dual treatment of glomerular filtration and albumin reabsorption may represent an effective treatment of salt-sensitive hypertension. 28404591 2017
Entrez Id: 213
Gene Symbol: ALB
ALB
0.400 Biomarker group BEFREE Urinary albumin might be more attributable to CVD and all-cause mortality than HTN. 28472229 2017
Entrez Id: 213
Gene Symbol: ALB
ALB
0.400 Biomarker group BEFREE Relationship between subtle urinary albumin excretion and risk of incident hypertension: modification by glomerular filtration rate. 28933781 2017
Entrez Id: 213
Gene Symbol: ALB
ALB
0.400 Biomarker group BEFREE The development of hypertension was attenuated in anti-CD3 treated mice with SLE independently of changes in renal injury (assessed by urinary albumin). 28400152 2017
Entrez Id: 213
Gene Symbol: ALB
ALB
0.400 GeneticVariation group BEFREE The main outcome measures were estimated CKD prevalence (by serum creatinine-based estimated glomerular filtration rate (eGFR) and dipstick urine albumin); and estimated prevalence of CKD risk factors (diabetes, hypertension and obesity). 28056873 2017